BACKGROUND All recipients of kidney transplantation, especially those with posttransplant malignancy, are at risk of long-term graft failure. OBJECTIVES The purpose of our study was to evaluate the risk factors associated with graft survival after diagnosis of malignancy. PATIENTS AND METHODS To reach this purpose, we conducted a historical cohort study in Iran and 266 cases with posttransp...

background and purpose: invasive candidiasis (ic) is a significant cause of morbidity and mortality in patients with hematologic disorders and bone marrow transplant recipients. rapid, specific and sensitive test for the timely accuracy in immunocompromised patients to reduce mortality rates and prevent ic progress is necessary. we established a real-time pcr assay on blood for the diagnosis an...

Objective: Kidney transplantation is the best treatment option for patients with end-stage renal disease. However, transplant recipients have been shown to a higher risk of cancer than general population. This has attributed malignancies associated immunosuppression in these patients. In our study, we aimed investigate incidence post-transplant malignancy, duration development and factors kidne...

Patients with the rare primary immunodeficiency due to dedicator of cytokinesis 8 (DOCK8) mutations commonly suffer from atopic disorders, recalcitrant viral infections, potential malignancy, and early mortality. Even in absence skin lesions, DOCK8-deficient has been previously shown have an abundant virome. Hematopoietic stem cell transplantation (HSCT) is potentially curative for this disease...

Abstract Background The clinical characteristics of mammalian target rapamycin (mTOR) inhibitors use in heart transplant (HT) recipients and their outcomes have not been well described. Methods We compared patients that received mTOR within the first 2 years after HT to did by inquiring United Network for Organ Sharing database between 2010 2018. primary endpoint was all-cause mortality with re...

BACKGROUND The purpose of the study was to describe clinical characteristics and long-term survival of patients undergoing combined heart-kidney transplant in a single center. METHODS We conducted a retrospective analysis of 22 consecutive patients who underwent combined heart-kidney transplant at our institution between 1995 and 2013. Long-term outcomes were analyzed by means of the Kaplan-M...