neuroinflamation occurring after traumatic brain injury (tbi) is a complex phenomenon comprising distinct cellular and molecular events involving the injured cerebral tissue. mechanical injury to adult rat brain elucidated the accumulation in the affected area of trophic activity. in the tissue adjacent to the injury, trophic titers began to rise after the lesion. this study aimed to determine ...

Main results 48% of participants had an axis I disorder that began after traumatic brain injury. 62% had an axis I disorder during their lifetimes. Common new disorders following traumatic brain injury were major depression (27%), alcohol abuse or dependence (12%), panic disorder (8%), specific phobia (8%) and psychotic disorders (7%). 23% had at least one personality disorder. Conclusions Trau...

Children with traumatic brain injury are reported to have deficits in performance monitoring, but the mechanisms underlying these deficits are not well understood. Four performance monitoring hypotheses were explored by comparing how 28 children with traumatic brain injury and 28 typically developing controls (matched by age and sex) performed on the stop-signal task. Control children slowed si...

BACKGROUND Traumatic brain injuries are common and costly to hospital systems. Most of the guidelines on management of traumatic brain injuries are taken from the Brain Trauma Foundation Guidelines. This is a review of the current literature discussing the evolving practice of traumatic brain injury. DATA SOURCES A literature search using multiple databases was performed for articles publishe...

BACKGROUND It is known that the risk of death in elderly patients with moderate to severe traumatic brain injury is increased. However, the relationship between mild traumatic brain injury and death has never been established. We investigated the mortality rates of older patients with mild traumatic brain injury in Taiwan to evaluate if there is a higher risk of death compared with the general ...

BACKGROUND It is known that the risk of stroke in patients with traumatic brain injury might be increased. However, the relationship between mild traumatic brain injury and ischemic stroke has never been established. We conducted a study of patients in Taiwan with mild traumatic brain injury to evaluate if they had a higher risk of stroke compared with the general population. METHODS We utili...

INTRODUCTION Exposure to adverse childhood experiences (ACEs) is a significant risk factor for physical and mental illnesses later in life. Concussion or traumatic brain injury is a challenging condition where preinjury factors may interact to affect recovery. The association between ACEs and traumatic brain injury/concussion is not well mapped in any previous reviews of the literature. Using a...

Traumatic brain injury is a substantial cause ofmorbidity and mortality in the UK. An estimated 11 000 people per year sustain a severe traumatic brain injury, mostly between ages 15 and 29 years. Patients with severe traumatic brain injury have a high mortality rate (30-50%) and many survivors will have persistent severe neurological disability. Prompt identification and appropriate early mana...

Introduction: Following a traumatic brain injury (TBI), the excessive release of proinflammatory cytokines is major cause of cerebral edema that can cause permanent neuronal loss. This study examined the changes in brain concentrations of proinflammatory cytokines IL-1, IL-6, TNF-α and TGF- after different doses of estrogen or progesterone treatment in brain-injured rats at 6 and 24 h post...

Traumatic brain injury is defined as trauma to the head that can cause physical, intellectual, emotional, social or behavioral changes. one of leading causes morbidity and mortality worldwide. Brain disorders are among most common in neurology. brain, it accounts for 2 15% all injuries. This study aims determine histopathological picture hemorrhage rats after experiencing traumatic analyze rela...