Background: Vitamin D, a steroid hormone, has critical roles in human health. The available data thus identify vitamin D as an important substance in processes involved in reproductive success and thereby suggest pathophysiological mechanisms for reproductive compromise in the setting of vitamin D deficiency. Realizing the prevalence of vitamin D insufficiency in our country, we hypothesized th...

Introduction: Multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis (EAE), is a chronic inflammatory diseases and degenerative myelin in the CNS. With respect to being the main cause of this disease is unknown; the most common treatments for the disease (MS) with the aim of suppressing harmful inflammatory responses are used. Neuro transmitters having immunosup...

abscess formation following intramuscular injections is rare and they are most commonly seen in immunocompromised individuals. in this case series we present a cohort of three patients presented to us in a critically ill condition with an abscess due to intramuscular injection. vancomycin resistant staphylococcus aureus was isolated from all three patients. these patients posed a major challeng...

intrathecal injection of sufentanil with adrenalin was performed in 45 cases (20 female, 25 male age range: 18-40 years). all injections were performed in the sitting position, with a number 20 intrathecal needle immersed in adrenalin. the cases were observed for 72 hours. maximum duration of analgesia was 12 hours (60%) and the minimum was 3 hours (13.3%). this method reduces the need for repe...

introduction: the aim of this randomized-controlled clinical trial was to assess the effect of intraligamentary (pdl) injection of dexamethasone on onset and severity of post-treatment pain in patients with symptomatic irreversible pulpitis. methods and materials: a total number of 60 volunteers were included according to the inclusion criteria and were assigned to three groups ( n =20). after ...

objective: to evaluate the plasma creatine phosphokinase (cpk) level after injection of methotrexate (mtx) as a predictor of treatment success in ectopic pregnancy (ep). materials and methods: one hundred women treated with single dose of methotrexate for ectopic pregnancy were evaluated in a prospective study, for cpk and ß-subunit of human chorionic gonadotropin (ß-hcg) levels. they received ...

Background: Formaldehyde (FA) is a suspected reproductive toxicant, which may cause significant adverse effects on human reproductive system. Given to its widespread use in occupational setting, and more recently, in several industries related to construction and household products, everyone may be exposed to FA. This study was designed to determine the effect of FA and to investigate possible ...

AIM This study was performed to determine the effect of a single, large, intramuscular injection of vitamin D post-partum on glucose tolerance and insulin resistance in women with gestational diabetes. METHODS Forty-five participants in a randomized controlled trial on gestational diabetes mellitus were divided into an intervention group and a control group. Only subjects in the intervention ...

It is believed that some pitfalls in the treatment of epilepsy including serious side effects of medications and drug resistance may be resolved by natural compounds. Auraptene is a natural coumarin that is found in many plants, particularly citrus peel. We hypothesized that auraptene might have anticonvulsant properties. Kindling was induced by repeated intraperitoneal (IP) injections of penty...