In cluster randomized trials (CRTs), individuals belonging to the same cluster are very likely to resemble one another, not only in terms of outcomes but also in terms of treatment compliance behavior. Although the impact of resemblance in outcomes is well acknowledged, little attention has been given to the possible impact of resemblance in compliance behavior. This study defines compliance in...

OBJECTIVE To evaluate the efficacy of "compliance therapy" for improving adherence to prescribed drug treatment among patients with schizophrenia. DESIGN Randomised controlled trial. SETTING Urban catchment area psychiatric service. PARTICIPANTS 94 consecutive admissions of patients with schizophrenia, 56 agreed to participate. INTERVENTION Compliance therapy and non-specific counsellin...

Community acceptance of and compliance with annual ivermectin treatment in Shao, a sub-urban community in Kwara State, Nigeria, were remarkably high. Of 890 subjects from 204 randomly selected households, 832 (93.5%) had taken ivermectin at least once during the six-year treatment period. An average community acceptance rate (ACAR) of 88.77% (range 85.4 - 91.9%) was recorded during this period;...

Of 62 men with non-gonococcal urethritis who entered a study to assess compliance with treatment with oxytetracycline, only 33 could be evaluated. Traditional methods (interview and the absence of oxytetracycline in the urine) showed incomplete compliance in nine. Use of low dose phenobarbitone as a pharmacological marker showed incomplete compliance in a further five patients. In addition, phe...

Abstract Background Iron overload is a major problem in patients with major thalassemia. An effective and safe iron chelator protocol with high compliance rate plays an important role in treatment of these patients. This study was done to assess the efficacy and safety of the sequential deferoxamine and deferasirox protocol in major thalassemia patients in Khuzestan province, Iran. Material ...

''Compliance and patching and atropine amblyopia treatments " – Reply to Letter to the Editor Dear Editor, I would like to thank Drs. Loudon, Tjiam, and Simonsz for their constructive criticism of my review article entitled ''Compliance and patching and atropine amblyopia treatments " (Wang, 2015). As noted in their letter, several summary conclusions in this review article that were derived fr...