The aim of this study was to perform a systematic review and meta-analysis to examine the effect of systemic antibiotics in the periodontal treatment of smokers. The selection criteria were as follows: controlled randomized clinical trials; studies published in English; studies with smoker patients diagnosed with chronic periodontitis; patients without systemic diseases; studies that used syste...

This study investigated the effect of non-surgical periodontal therapy on the composition of subgingival microbiota of patients with chronic kidney disease (CKD). Sixteen CKD pre-dialysis individuals (CKD) and 14 individuals without clinical evidence of kidney disease (C) presenting chronic periodontitis were treated by scaling and root planing. Subgingival samples were collected from each pati...

BACKGROUND To evaluate in patients with aggressive periodontitis (AgP) the effect of nonsurgical periodontal treatment in conjunction with either additional administration of systemic antibiotics (AB) or application of photodynamic therapy (PDT) on the gingival crevicular fluid (GCF) concentration of matrix metalloproteinases 8 and 9 (MMP-8 and -9). METHODS Thirty-six patients with AgP were i...

Recently discovered interleukin 29 (IL-29) has antiviral properties and its production is induced by herpes viruses. This study was aimed at analyzing the effect of non-surgical periodontal treatment on IL-29 levels in gingival crevicular fluid (GCF) of chronic and aggressive periodontitis patients. A total of 60 participants were divided into healthy group (group 1; n=20), chronic periodontiti...

BACKGROUND The aim of this study was to analyze the CO2 laser effects on root surfaces affected by periodontal disease in comparison to scaling and root planing for fibroblast attachment. METHODS Thirty single-rooted human teeth extracted because of advanced periodontal disease were included in this study. A total of 60 specimens, obtained from all selected teeth, were randomly assigned to 3 ...

background: accelerated partial breast irradiation via interstitial balloon brachytherapy is a fast and effective treatment method for certain early stage breast cancers however skin, chest wall and lung doses are correlated with toxicity in patients treated with breast brachytherapy. objective: to investigate the percentage of the dose received by critical organ (skin), thermoluminescence dete...

Periodontitis is a complex disease that involves the loss of attachment around teeth resulting from action of microorganisms and the response of the host to these organisms. The basic treatment of chronic periodontitis is a mechanical debridement of periodontal pockets by Scaling and root planing (SRP) in combination with efficient plaque control. The effectiveness of mechanical debridement of ...

gene therapy consists of the introduction of genetic material into cells for a therapeutic purpose. the understanding of the basics of the molecular and cellular mechanisms in disease treatments has resulted in the development of high-tech gene transfer materials with improved therapeutic efficacy. based on the results of more than 2000 clinical trials to date, gene therapy is going to be inclu...

In this paper, the author has reviewed the microbial & clinical impacts of the one-stage full-mouth disinfection and quadrant scaling root planing in Periodontics. Periodontal diseases are one of the most common in the oral cavity and have an infectious nature triggered by pathogenic microorganisms that first lead to gingivitis and may develop to periodontitis and, if not treated, to tooth loss...