Recently, we have reported that the cytokines -melanocyte-stimulating hormone ( -MSH) and transforming growth factor2 (TGF2) work in synergy to induce the activation of regulatory T (Treg) cells. When we used -MSH and TGF2 to generate ocular autoantigen-specific Treg cells and adoptively transferred them into mice susceptible to experimental autoimmune uveoretinitis (EAU), there was suppression...

Gastric trefoil peptides mediate mucosal repair by stimulating cell migration, inhibiting apoptosis and inflammation, and likely augmenting the barrier function of mucus. One of these, tff1, is a gastric-specific tumor suppressor gene, which when repressed is associated with gastric cancer progression. IL-6 family cytokines play an important role in maintaining gastric homeostasis by regulating...

AIM The purpose of this study was to evaluate the diagnostic value of trefoil factor family 3 (TFF3) for the early detection of colorectal cancer (CC). METHODS Serum TFF3 and carcino-embryonic antigen (CEA) were detected in 527 individuals, including 115 healthy control (HC), 198 colorectal adenoma (CA), and 214 CC individuals in the training group. RESULTS Serum TFF3 showed no significant ...

We give a Dehn surgery characterization of the trefoil and the figure eight knots. These results are gotten by combining surgery formulas in Heegaard Floer homology from an earlier paper with the characterization of these knots in terms of their knot Floer homology given in a recent paper of Ghiggini.

The protein deleted in malignant brain tumors (DMBT1) and the trefoil factor (TFF) proteins have all been proposed to have roles in epithelial cell growth and cell differentiation and shown to be up regulated in inflammatory bowel diseases. A panel of monoclonal antibodies was raised against human DMBT1(gp340). Analysis of lung washings and colon tissue extracts by Western blotting in the unred...

Prep lan t soil appl ica t ions of g r a n u l a r p h e n a m i p h o s effectively reduced Pratytenchus penetrans in soil d u r i n g the seeding year a nd 1 year after, and in the roots of birdsfoot trefoil 2 )'ears af ter seeding. Forage yields were increased in t he season fol lowing appl ica t ion of p h e n a m i p h o s , bu t s tands of p l a n t s / m s were not grea ter (P = 0.05) t ...