In the title compound, C(25)H(16)ClN(3)O, the anthryl and chloro-phenyl substituents are on opposite sides of the triazole ring. The anthryl and benzene mean planes are aligned at 83.35 (2) and 89.09 (2)°, respectively, with respect to the triazole ring.

Ligand redistribution reactions are well documented for silver(I) N-heterocyclic carbene (NHC) complexes of the type [AgX(NHC)] (X = halido ligand), but only two reports have been described in the literature for gold analogues of the general formula [AuX(NHC)]. In both cases, the NHCs in question were exceptionally strong donors. To probe the dependence of ligand redistribution processes on NHC...

In the title compound, C(11)H(9)BrN(4)S, the 1,2,4-triazole ring is essentially planar (r.m.s. deviation = 0.020 Å) and makes a dihedral angle of 29.1 (5)° with the bromo-benzene ring. The 3,6-dihydro-1,3,4-thia-diazine ring adopts a twist-boat conformation. In the crystal, mol-ecules are linked by C-H⋯N inter-actions into sheets lying parallel to the (010) plane. The same N atom accepts two su...

Post-translational modifications (PTMs) are used by organisms to control protein structure and function after translation, but their study is complicated roles not often well understood as PTMs difficult introduce onto proteins selectively. Designing reagents that both good mimics of PTMs, also only modify select amino acid residues in challenging. Frequently, a chemical warhead linker used, cr...

substituted 1, 2, 4- triazoles have shown multiple biological activities such as anti-inflammatory, anti fungal, etc. 5-mercapto triazoles were prepared from the potassium dithiocarbazinates. these triazoles were used for preparation of different derivatives by two different schemes. in the first scheme the mannich bases were prepared from 5- marcapto-s triazole quinazolines. the 5-marcato-s-tr...

Keywords: endothelial dysfunction, NO, nitrosative stress, reduced thiols, S-derivatives of 1,2,4-triazole

The aim of the work. 1,2,4-triazole derivatives possess a wide range pharmacological activity, so they are used for development drugs and active pharmaceutical ingredients. Due to reactivity 1,2,4-triazoles there many options their further structural modification on different reaction centers. Therefore, work was obtain new S-substituted 1,2,4-triazole-3-thiols, study physicochemical parameters...

Only few efficient methods for the preparation of polyazoles containing three or four nitrogen atoms in each azole cycle exist. We have developed a novel synthetic strategy that allows sequential assembly 1,2,3-triazole, 1,2,4-triazole, and tetrazole fragments into new stable polyazole. Along strategy, some known procedures been optimized to achieve better conversion, selectivity, and, general,...

in order to investigate the characteristics of in vitro microtuberization of potato cv. agria in response to the two triazole anti-gibberellin, paclobutrazole and uniconazol, two independent experiment in five concentrations (0, 0.08, 0.16, 0.32, 0.64 mg/l) of each compound were carried out with four replications for each treatment in a completely randomized design. in this experiment percent o...

Chemical ligation of long synthetic alkyne and azide functionalised oligonucleotides by the CuAAC reaction is a new strategy for overcoming the size limit of DNA and RNA synthesised by solid-phase phosphoramidite chemistry. Remarkably, the latest triazole linker formed by this method (Fig. 1a) is correctly readthrough by DNA polymerases and is functional in bacteria. In order to investigate the...