BACKGROUND A novel, bead-based flow cytometric assay was developed for simultaneous determination of antibody responses against Toxoplasma gondii and Trichinella spiralis in pig serum. This high throughput screening assay could be an alternative for well known indirect tests like ELISA. One of the advantages of a bead-based assay over ELISA is the possibility to determine multiple specific anti...

To assess the possibility that increases in UV-B exposure on the earth's surface could lead to impaired resistance to several infectious diseases, we studied the effect of UV-B exposure on resistance against Trichinella spiralis. Wistar rats, orally infected with T. spiralis larvae, were exposed to suberythemal doses of UV-B radiation daily for 5 days at different time periods before or after i...

Trichinella spiralis is unique among all known nematodes in being the only species to occupy an intra-multicellular niche in the body of its host. Like developing tumours they also need to recruit new blood vessels towards the developing nurse cells to meet the ever-growing demand of nutrients. Like viruses they highjack the cell machinery and physiology so as to ensure their growth. Thus, inte...

Two direct methods for the diagnosis of trichinellosis were compared: trichinoscopy and artificial digestion. Muscles from 17 wistar rats, orally infected with 500 Trichinella spiralis encysted larvae were examined. From each of the following muscles: diaphragm, tongue, masseters, intercostals, triceps brachialis and cuadriceps femoralis, 648,440 larvae from 1 g samples were recovered. The line...

The possibility that an unrelated disease process may alter the reaction to the trichinella skin test was uncovered in the course of an investigation on the incidence of trichinosis. A higher percentage of positive skin reactions to trichinella antigen (18.3 per cent) was obtained in 674 patients with active tuberculosis confined in 3 sanatoria, than was found in 335 patients without tuberculos...

Background Endemic human trichinellosis has been rare in Norway, Sweden and Finland. In Norway the last outbreak involving five persons is from 1953 and before that there were reported six epidemics with 711 patients since 1881 (reference in [1]). In Sweden 10 outbreaks involving 504 patients were documented 1917-1969 (reference in [2]). In Finland only eight human cases have been reported sinc...