Jatropha gossypiifolia L. (Euphorbiaceae) is widely used in popular medicine. However, further toxicological studies are necessary for its reliable use. The present study aimed to evaluate the cytotoxic, genotoxic, and mutagenic effects of ethanolic and aqueous leaf extracts of J. gossypiifolia, using the test system Allium cepa. In addition, the phytochemical profile of the extracts was also o...

A novel approach of modeling gas-particle partitioning using polyparameter linear free energy relationships (ppLFERs) is implemented into three different multimedia box models (the OECD Pov and LRTP screening tool (The Tool), ChemRange, and CliMoChem) and compared to approaches based on the octanol-air partition coefficient (K(OA)). In all three multimedia models, calculated overall persistence...

Dinitroanilines (oryzalin, trifluralin, ethafluralin) disrupt microtubules in protozoa but not in vertebrate cells, causing selective death of intracellular Toxoplasma gondii parasites without affecting host cells. Parasites containing alpha1-tubulin point mutations are dinitroaniline resistant but show increased rates of aberrant replication relative to wild-type parasites. T. gondii parasites...

An advantageous plasma-catalytic setup was developed and applied towards the degradation of trifluralin in soil. For first time, TiO2 ZnO catalysts were compared when employed conjunction with micro-discharges generated directly into interconnected soil channels. In presence catalysts, a significant increase efficiency observed; after 5 min, increased from 66.5% (plasma alone) to 94.2% 93% addi...