 Inhaled phosphine is absorbed rapidly from the lungs and distributed round the body  Inhaled or ingested zinc, aluminium and magnesium phosphides release phosphine into the respiratory tract and stomach; zinc phosphide can be absorbed intact from the gut  Dermal absorption of phosphine or phosphides is not considered a significant route of exposure  The majority of absorbed phosphine is ex...

Phosphine (hydrogen phosphide, PH3) is the fumigant most widely used to protect stored products from pest infestation. Despite the importance of this chemical, little is known about its mode of action. We have created three phosphine-resistant lines (pre-1, pre-7, pre-33) in the model organism C. elegans, with LC50 values 2, 5, and 9 times greater than the fully susceptible parental strain. Mol...

Phosphine fumigations under superatmospheric oxygen levels (oxygenated phosphine fumigations) were significantly more effective than the fumigations under the normal 20.9% atmospheric oxygen level against western flower thrips [Frankliniella occidentalis (Pergande)] adults and larvae, leafminer Liriomyza langei Frick pupae, grape mealybug [Pseudococcus maritimus (Ehrhorn)] eggs, and Indianmeal ...

--Gaseous phosphine was found to inhibit biogas formation during the anaerobic fermentation of swine manure. A logarithmic dose-response correlation was obtained with 50% inhibition at a phosphine concentration of approximately 150 ppm. Anaerobic fermentation of acetate and yeast extract measured by biogas formation were not affected at concentrations up to 1000 ppm. Despite the relative tolera...

Two synthetic strategies for incorporating diiron analogues of [FeFe]-hydrogenases into short peptides via phosphine functional groups are described. First, utilizing the amine side chain of lysine as an anchor, phosphine carboxylic acids can be coupled via amide formation to resin-bound peptides. Second, artificial, phosphine-containing amino acids can be directly incorporated into peptides vi...

The effects of different types and concentrations of electron donors (glucose, starch, methanol and sodium acetate) on the formation of phosphine from anaerobic activated sludge that has been domesticated for a prolonged period were studied in small batch experiments. The results show that types and concentrations of electron donor have significant effects on the production of phosphine from an...

The objectives of this work were to assess phosphine resistance in insect populations (Tribolium castaneum, Rhyzopertha dominica, Sitophilus zeamais and Oryzaephilus surinamensis) from different regions of Brazil and to verify if the prevailing mechanism of phosphine resistance in these populations involves reduced respiration rates. Sixteen populations of T. castaneum, 15 of R. dominica, 27 of...

The red flour beetle is a cosmopolitan pest of stored grain and stored grain products. The pest has developed resistance to phosphine, the primary chemical used for its control. The reproductive output of survivors from a phosphine treatment is an important element of resistance development but experimental data are lacking. We exposed mated resistant female beetles to 0.135 mg/L of phosphine f...

The manufacture and application of aluminium phosphide fumigants pose risks of inhalation exposure to phosphine gas. This article presents a case report of suspected inhalation exposure to phosphine gas in a manufacturing facility for aluminium phosphide fumigants, which was associated with acute dyspnoea, hypotension, bradycardia and other signs of intoxication. These symptoms resolved within ...

background: aluminum phosphide (alp) poisoning is one of the most life threatening emergencies. in this study, demographic characteristics, clinical profiles and outcomes of a series of patients presented with alp poisoning in north iran are described. methods: the study was a retrospective descriptive medical chart review of alp poisoned patients who were admitted to internal ward of imam khom...