The continued spread of multidrug-resistant (MDR) tuberculosis and extensively drug-resistant tuberculosis poses a major threat to global tuberculosis control. Treatment is complex and requires longer use of more-expensive, less effective, and toxic anti-tuberculosis drugs, which results in high morbidity and mortality. The poor treatment outcomes and the slow progress in the development and ev...

introduction: tuberculosis (tb), with different types of respiratory tract involvements, has a high rate of mortality all around the world. endobronchial involvement, which is a slightly common tuberculous infection, requires special attention due to its severe complications such as bronchostenosis. aim of study of this study was describes, one type of pulmonary tuberculosis with less diagnosed...

BACKGROUND Isoniazid has been the backbone of tuberculosis chemotherapy for 6 decades. Resistance to isoniazid threatens the efficacy of treatment of tuberculosis disease and infection. To inform policies around treatment of tuberculosis disease and infection in children, we sought to estimate both the proportion of child tuberculosis cases with isoniazid resistance and the number of incident i...

persons infected with the human immunodeficiency virus (hiv) are particularly susceptible to tuberculosis, either by latent infection reactivation or by a primary infection with rapid progression to active disease. this study was done to determine the frequency of tuberculosis infection among iranian patients with hiv/aids. a total of 262 hiv/aids patients attending all three hiv/aids health ca...

BACKGROUND The success of the current treatment regimen for multidrug-resistant (MDR) tuberculosis is poor partly owing to a high default rate. Many studies have explored predictors of poor outcomes, but very few have assessed the effects of treatment interruptions on treatment outcomes for MDR tuberculosis. METHODS We conducted a retrospective analysis among patients with MDR tuberculosis en...

Reporting of the «transferred out» outcome leads to significantly worse treatment results tuberculosis patients treated in institutions Federal Penitentiary Service Russia. The objective: investigate patients’ routes that led reporting outcome, and propose measures reduce risk this outcome. Subjects Methods. We studied places registration 1,496 pulmonary registered for 2019 (new cases relapses)...

The first structurally authenticated [2+2] cycloaddition products of any transition metal hydrazide complexes are reported; cycloaddition products of transition metal hydrazides with alkynes and heteroalkynes have been obtained for the first time; these are the first structurally authenticated cycloaddition products for any transition metal M=NNR(2) functional group.

T he recently published World Health Organization (WHO) 2011 Global Report [1] provides important new information on the status of the tuberculosis (TB) epidemic and better estimates are now available on different indicators of TB control. These were possible thanks to new methodologies used to measure the disease, producing more precise figures on mortality, number of children orphaned by TB, ...

BACKGROUND Despite the existence of national tuberculosis guidelines (NTG) in Ethiopia, the incidence and prevalence of tuberculosis did not decline markedly. Audits could attempt to determine whether or not healthcare professionals actually implemented these guidelines, as non-implementation could contribute to suboptimal tuberculosis treatment outcomes. AIM To evaluate healthcare providers'...