Monozygotic twins, identical by serological studies, with Huntington's disease are described who were raised in separate households from birth. Age at onset, landmarks of the disease, and behavioural abnormalities were strikingly similar. Previously reported twin studies in Huntington's disease are reviewed. Twin data support the hypothesis that age at onset and several other clinical features ...

Case Report Our patient, the second of a set of twins, was a Chinese baby girl delivered small for gestational age at 28+3 weeks via emergency caesarian section with a birth weight of 730 g. The pregnancy was complicated by twin-twin transfusion with discrepant growth and maternal hyperthyroidism. A previous sibling had no history of GBS infection but the mother was not screened for GBS via vag...

AIM Report of a case of successful twin pregnancy following liver transplantation. PATIENT AND METHOD A 42-year-old nulliparous-woman was subjected to an orthotopic liver transplantation due to Budd-Chiari syndrome. Sixteen months after the transplantation, an ultrasonography revealed twin pregnancy. Her prenatal course was uneventful, except for mild arterial hypertension. The immunosuppress...

This study aimed to evaluate the prevalence of birthweight discordance among twins, to determine the risk cut-off point for birthweight discordance, and to clarify whether perinatal deaths are aggravated by birthweight discordance or by low birthweight itself. A population-based analysis of all twins born between 1995 and 1999 in Japan was conducted using data collected from national birth, dea...

In a multicentre study on perinatal HIV-I infection including 1493 children born from 1471 pregnancies to 1415 infected mothers, 22 twin pairs and 56 sibships (115 children) were recorded. The frequency of twin pregnancies was 1.5 (22/1471) and 3.9% (56/1415) seropositive women had more than one at risk pregnancy. In 18 twin pairs with a known infection status nine of the 36 children (25%) were...

BACKGROUND Although management of twin deliveries has been a topic of discussion for decades, a consensus on how to deliver twins is lacking. The objective of this study was to examine short-term neonatal outcome of the second twin delivered by cesarean section after vaginal delivery of the first-born twin (combined delivery) and to identify predictors of combined delivery. METHODS This study...

A monochorionic twin pregnancy is one in which both babies are dependent on a single, shared placenta. Around one-third of twin pregnancies in the UK have monochorionic placentas. Monochorionic placentation can also occur in higher-order multiples. There has been a recent increase in all types of multiple pregnancies with the increasing use of assisted reproductive techniques. Monochorionic (MC...

OBJECTIVE To evaluate the influence of gestational diabetes mellitus on weight discrepancy in twin pregnancies. METHODS 200 twin pregnancies were included in the study. 157 nondiabetic pregnant women with twin gestations and 43 twin pregnancies with gestational diabetes mellitus (GDM) with viable fetuses born after 24 weeks of gestation were enrolled. Influence of maternal age, body-mass-inde...

A monochorionic twin pregnancy is one in which both babies are dependent on a single, shared placenta. Around one-third of twin pregnancies in the UK have monochorionic placentas. Monochorionic placentation can also occur in higher-order multiples. There has been a recent increase in all types of multiple pregnancies with the increasing use of assisted reproductive techniques. Monochorionic (MC...

BACKGROUND The relationship between congenital hypothyroidism (CH) and multiple pregnancy has not been fully studied in Japan. METHODS Complete nationwide data of assisted reproductive technology (ART) in Japan from 2005 to 2009 presented by the Japan Society of Obstetrics and Gynecology, which include information on CH and birth defects were used for analyses. Diseases were reclassified acco...