BACKGROUND Epithelial-mesenchymal transition (EMT) is associated with tumor hypoxia. EMT is regulated, in part, by the action of TWIST, which inhibits of E-cadherin expression and may interfere with the p53 tumor-suppressor pathway. METHODS We examined the expression of TWIST, E-cadherin, hypoxia-inducible factor 1α (HIF1α), and p53 by immunohistochemistry in 123 cases of ovarian epithelial c...

Evidence suggests that over-expression of TWIST, an epithelial-mesenchymal transition inducer, might have a correlation with cancer progression and chemoresistance. However, its roles in radioresistance of cancer have rarely been reported. High TWIST expression was detected in nasopharyngeal carcinoma (NPC) and associated with poor prognosis. Thus, in the present study, we aimed to determine wh...

A top-down page segmentation technique known as the recursive X-Y cut decomposes a document image recursively into a set of rectanguzar blocks. This paper proposes that the recursive X-Y cut be implemented using bounding bozes of connected components of black pixels instead of using image pizels. The advantage is that great improvement can be achieved in computation. In fact, once bounding boxe...

Crystalline arrays of proteinaceous subunits forming surface layers (S-layers) are now recognized as one of the most common outermost cell envelope components of prokaryotic organisms. The surface layer protein of Lactobacillus acidophilus ATCC4356 is composed of a single species of protein of apparent molecular weight of 43-46 KDa. Considering the Lactobacillus acidophilus ATCC4356 having the ...

Medaka twist, a basic helix-loop-helix (bHLH) transcription factor, is expressed in the sclerotome during embryogenesis. We previously established a line of twist-EGFP transgenic medaka, whose EGFP expression is regulated by the twist promoter; therefore, we could observe the behavior of sclerotomal cells in vivo. In the transgenic medaka embryos, EGFP-positive sclerotomal cells migrated dorsal...

This study aimed to examine HIF-2α, TWIST, and CXCR4 expression in papillary thyroid carcinoma (PTC) and assesses the association of their expression with clinicopathological indicators. HIF-2α, TWIST, and CXCR4 protein expression in 129 PTCs, 61 nodular hyperplasia, and 118 normal thyroid tissue specimens was analyzed using immunohistochemistry. The protein expression levels of these three mol...

In this particular isospin combination of structure functions the contribution of twist-2 operators cancels out exactly and twist-4 contributions are dominant. It is remarkable that in the large Nc limit the twist-4 distribution function of quarks in the pion can be reduced to a convolution of twist-2 pion distribution amplitudes. 2. One can read the contribution of four-quark twist-4 operators...

We present a higher-twist production mechanism for η c and χ J charmonium at large momentum fraction x F in pion-nucleon collisions. The higher-twist contribution is essentially independent of x F and therefore becomes dominant at large x F , where the leading-twist contribution falls off as (1 − x F) 3. We show that the higher-twist mechanism produces longitudinally polarized χ 1 and χ 2. For ...

The twist number of a plane graph associated with a link’s checkerboard coloring is defined. The twist number of any planar pseudograph is shown to be determined by the Tutte polynomial. This allows the definition of twist number to be extended to non-planar graphs, for which the twist number is also determined by the Tutte polynomial. As a corollary, the twist number of an alternating link is ...