Diabetes mellitus is a complex syndrome characterized by hyperglycaemia, thickening of basement membrane of the capillaries and a variety of late complications including accelerated atherosclerosis, retinopathy, nephropathy and neuropathy. Primary diabetes mellitus is broadly divided into type I or the insulin-dependent diabetes mellitus (IDDM) and type 2 or the non-insulin-dependent diabetes m...

abstract background: better control of blood sugar and reduction of diabetes complications through insulin therapy could convince people to choose this method. however, patients might refuse insulin therapy due to its painful injection, limitations in daily activities, and hypoglycemia. thus, insulin therapy could have both positive and negative effects on patients’ quality of life (qol). there...

Introduction: Antioxidant agents have beneficial effects in diabetes mellitus. Daucus carota seeds extract has been shown to possess antioxidant activity. In this study, the effect of the methanolic extract of Daucus carota seeds on carbohydrate metabolism and morphology of pancreas was investigated in type I diabetic male rats. Methods: Type I diabetes mellitus was induced in male Wistar ...

The mitochondrion has been implicated in the development of diabetic cardiomyopathy. Examination of cardiac mitochondria is complicated by the existence of spatially distinct subpopulations including subsarcolemmal (SSM) and interfibrillar (IFM). Dysfunction to cardiac SSM has been reported in murine models of type 2 diabetes mellitus; however, subpopulation-based mitochondrial analyses have no...

expression of anti-insulin autoantibodies of man and the NOD mouse: evidence for early determination of subsequent diabetes. Noordzij JG, et al. Development of type 1 diabetes despite severe hereditary B-lymphocyte deficiency. al. Immunological abnormalities in islets at diagnosis paralleled further deterioration of glycaemic control in patients with recent-onset type I (insulin-dependent) diab...

abstract introduction: in recent years, many studies employed and found an association between type 2 diabetes mellitus and colorectal cancer. although increased risk of colorectal cancer in individuals with non insulin dependent diabetes mellitus (niddm) has been observed in previous studies, limited information is available on the colorectal cancer associated with niddm in iran. the purpose o...

Context Multiple consensus statements decree that women with diabetes mellitus should have comparable birth outcomes to women without diabetes mellitus; however, there is a scarcity of contemporary population-based studies on this issue. Objective To examine temporal trends in obstetric interventions and perinatal outcomes in a population-based cohort of women with type 1, type 2, or gestatio...

1. Aird I, Bentall HH, Roberts JA. A relationship between cancer of stomach and the ABO blood groups. Br Med J 1953;1:799-801. 2. Aird I, Bentall HH, Mehigan JA, Roberts JA. The blood groups in relation to peptic ulceration and carcinoma of colon, rectum, breast, and bronchus; an association between the ABO groups and peptic ulceration. Br Med J 1954;2:315-21. 3. Discussion on the ABO blood gro...

abstract objective: globally, 3-5.2 percent of people suffer from diabetes which is one of the most serious metabolic disorders resulting in an increase in inflammatory biomarkers e.g. interleukin-6, tumor necrosis factor-alpha, and c-reactive protein. the aim of this study was to investigate the relationship between inflammation, oxidative stress and fasting blood glucose, lipid profile and an...