The amplitudes of spontaneous fluctuations in brain activity may be a significant source of within-subject and between-subject variability, and this variability is likely to be carried through into functional connectivity (FC) estimates (whether directly or indirectly). Therefore, improving our understanding of amplitude fluctuations over the course of a resting state scan and variation in ampl...

We examined the association between Neuroticism and mortality in 321 456 people from UK Biobank and explored the influence of self-rated health on this relationship. After ageand sexadjustment, a standard deviation increment in Neuroticism was associated with a 6% increase in all-cause mortality (hazard ratio = 1.06, 95% confidence interval = [1.03, 1.09]). After adjustment for other covariates...

Recent work has leveraged the unique genealogical structure and extensive genotyping (>30%) of the Icelandic population to perform long-range phasing (LRP), enabling accurate imputation and association analysis of rare variants in target samples typed on genotyping arrays. Here, we develop a fast and accurate LRP method, Eagle, that extends this paradigm to outbred populations by harnessing lon...

Background: Outcome in patients treated with haemodialysis (HD) is influenced by the delivered dose of dialysis. The UK Renal Association (RA) publishes Clinical Practice Guidelines which include recommendations for dialysis dose. The urea reduction ratio (URR) is a widely used measure of dialysis dose. Aim: To determine the extent to which patients received the recommended dose of HD in the UK...

ONERA}ElectroMagnetics & Radar Department, 2 Avenue E. Belin}BP 4025, 31055 Toulouse Cedex 4, France CNES, 18 Avenue Edouard Belin, 31401 Toulouse Cedex 4, France Dipartimento di Ellettronica e Informazione, Politecnico di Milano, 20133 Milano, Italy 4 Institute for Communications and Navigation, German Aerospace Research (DLR), D-82230 Wessling, Germany University of Bath, Bath BA2 7AY, U.K. E...

Pricing for mortgage and mortgage-backed securities is complicated due to the stochastic and interdependent nature of prepayment and default risks. This paper presents a unified economic model of the contingent claims and competing risks of mortgage termination by prepayment and default. I adopt a proportional hazard framework to analyze these competing and interdependent risks in a model with ...

We investigate the possibility of testing of the Einstein Equivalence Principle (EEP) using measurements of anomalous magnetic moments of elementary particles. We compute the one loop correction for the g−2 anomaly within the class of non metric theories of gravity described by the THǫμ formalism. We find several novel mechanisms for breaking the EEP whose origin is due purely to radiative corr...

The recent growth in personal multimedia communication devices being used for image transmission, have poised a challenge to protect such data against loss over mobile radio channels. This paper investigates several error protection schemes for robust transmission of JPEG2000 compressed imagery over mobile radio channels affected by various amounts of fading degradation. The nature of JPEG2000 ...

3 Institute of Psychiatry, Kings College, London, London, UK. 4 National Centre for Mental Health, Institute of Neurosciences and Mental Health, Cardiff University, Cardiff, UK. 5 Institute of Health and Wellbeing, General Practice and Primary Care, University of Glasgow, Glasgow, UK. Institute of Health and Wellbeing, Public Health, University of Glasgow, Glasgow, UK. 7 Division of Psychiatry,...

This is an interesting paper on a timely topic. As the authors argue, the recent global financial crisis has its roots in increased mortgage delinquencies caused by the bursting of the housing bubble in the United States. By what mechanism does such an increase in mortgage delinquencies affect the rest of the economy? And how should policy react to it? To address these issues, the authors devel...