While the effectiveness of clomiphene citrate in the treatment of oligo-ovulatory women has been demonstrated, its use in unexplained infertility remains controversial. In fact, expectant management, controlled ovarian stimulation plus intrauterine insemination and in vitro fertilization are among the possible treatments options for unexplained infertility. According to the most recent Cochrane...

BACKGROUND Artificial insemination (intrauterine insemination by husband or artificial insemination by husband) is often tried as first treatment for couples with unexplained infertility. Pertubation has previously proved to increase the chance of achieving pregnancy for these couples. The effect of pertubation on fertility can be mechanical as well as anti-inflammatory by using a substance tha...

The concentration of leukaemia inhibitory factor (LIF) was measured in uterine flushings obtained from normal fertile women, from women with unexplained infertility and from women who suffered recurrent miscarriage. In normal fertile women, LIF was not detected in flushings obtained on days luteinizing hormone (LH)+0 to LH+6 of the cycle, but concentrations gradually increased from day LH+7 to ...

Background: To establish importance of sperm DNA assessment in resolving the unexplained infertility problem. Materials and Methods: This article is based on the careful observation of texts and papers from 2000-2014 about the DNA damage assessment as a significant parameter of sperm function test. Results: Acidic Aniline blue, Sperm Chromatin Dispersion test(SCD), Malondialdehyde concentration...

BACKGROUND The aim of this randomized controlled trial was to compare the efficacy of extended letrozole regimen with clomiphene citrate in women with unexplained infertility undergoing superovulation and intrauterine insemination (IUI). METHODS Two hundred and fourteen patients with unexplained infertility were randomized into two equal groups using computer generated list and were treated b...

Introduction: Infertility, according to the WHO, is defined as failure to conceive after 12 months or more of regular unprotected sexual intercourse. As routine examinations and procedures are often unable to diagnose some pelvic pathologies, hysterolaparoscopy has become an important diagnostic modality to detect some hidden pelvic pathology in infertile females. Purpose: To determine the role...

introduction: infertility is a common complication present in 10-15% of the population. it causes serious problems for the family. there are different methods for evaluation and treatment of infertility. one of the routine tests is hysterosalpingography that was first used in1922 and with changes in types of contrast media and its techniques, it is the primary test for simultaneous evaluation o...