Benign myoclonic epilepsy of infancy is recognized as a generalized and idiopathic epilepsy by the International League Against Epilepsy. Unprovoked and reflex seizures have been reported in these patients. We describe a child diagnosed with benign myoclonic epilepsy of infancy, whose strictly unilateral and localized reflex myoclonias broaden the clinical spectrum of this idiopathic and genera...

Familial Mediterranean fever (FMF) is a systemic auto-inflammatory disorder characterized by seemingly unprovoked recurrent episodes of fever and localized inflammation usually involving the peritoneum, pleura and joints accompanied by a marked acute-phase response. The disease primarily affects populations living around the Mediterranean basin ( Jewish, Armenian, Arab, Turkish populations) but...

Unprovoked pathological laughter has been associated with various lesions arising from the hypothalamus, cerebral hemispheres, and brainstem. We report a 57-year-old man who presented with episodes of involuntary laughter with increasing frequency over the course of more than 4 years. A large left petroclival meningioma was found. His involuntary laughter has completely subsided after surgical ...

Setting: 56 sites in 5 countries. Patients: 822 patients ≥ 18 years of age (median age 54 y, 54% men) who had a first-ever, unprovoked, symptomatic deep venous thrombosis (DVT) (popliteal vein or more proximal leg veins) or acute pulmonary embolism (PE); and completed 6 to 12 months of anticoagulant therapy with warfarin. Exclusion criteria included > 2 years since VTE; other indications or con...