There is growing interest and commitment to the control of schistosomiasis and other so-called neglected tropical diseases (NTDs). Resources for control are inevitably limited, necessitating assessment methods that can rapidly and accurately identify and map high-risk communities so that interventions can be targeted in a spatially-explicit and cost-effective manner. Here, we review progress ma...

1 Schistosomiasis Control Initiative, Department of Infectious Diseases Epidemiology, St Mary’s campus, Faculty of Medicine, Imperial College London ; 2 MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom 3 Programme National de Lutte contre la Schistosomiase et les Vers Intestinaux, Ministère de la Santé...

BACKGROUND In Mozambique, schistosomiasis is highly endemic across the whole country. The Schistosomiasis Consortium for Operational Research and Evaluation (SCORE) coordinates a five-year study that has been implemented in various African countries, including Mozambique. The overall goal of SCORE was to better understand how to best apply preventive chemotherapy with praziquantel (PZQ) for sch...

Previous studies suggest that protective immunity against Schistosoma haematobium is primarily stimulated by antigens from dying worms. Praziquantel treatment kills adult worms, boosting antigen exposure and protective antibody levels. Current schistosomiasis control efforts use repeated mass drug administration (MDA) of praziquantel to reduce morbidity, and may also reduce transmission. The lo...

We determined the prevalence of urinary schistosomiasis in preschool children below the age of 5 years in three settlements around Oyan Reservoir in Ogun State, Nigeria. Of 209 children screened, 150 (71.8%) had an infection, with no significant difference between males and females; 42.9% of infants were infected. Both prevalence and intensity of infection increased significantly with age (P < ...

conclusions schistosomiasis is one of the major tropical and communicable diseases in the eastern mediterranean region (emr). however, today it is eliminated in iran by schistosomiasis control practices. results on the basis of our results, using a national program for schistosomiasis control based on active and passive case finding, snail control programs, education of people, conducting train...

BACKGROUND Schistosomiasis is a major health problem adversely affecting the health of vulnerable populations in Sudan. METHODS We conducted a school-based survey to estimate the prevalence of schistosomiasis in 36 villages in Southern Kordofan (SK) State. A total of 2,302 primary school students were recruited. Each student completed a questionnaire and submitted one urine and one stool samp...

We report a case of a 5-year-old girl who presented with a 3-month-long history of gross hematuria. She underwent an extensive laboratory workup (including an automated urine microscopy) and a kidney biopsy, all of which were within normal limits. While being prepared for a cystoscopy and more advanced imaging of the urinary tract, the family mentioned history of travel to a schistosomiasis end...

The operational and diagnostic performance of a two-step method for the cost-effective screening of urinary schistosomiasis was investigated in the Kilosa District of east-central Tanzania. In the first step a simple questionnaire was administered to 15,073 primary schoolchildren by their class teachers over a 4-week period. The answers to the questionnaires had a high negative predictive value...

BACKGROUND Schistosomiasis is a debilitating disease, infects millions of people in tropical and subtropical regions. This study assessed the situation of the urinary schistosomiasis among schoolchildren of the Alsaial Alsagair village, Sudan. METHODS A cross-sectional survey was carried out in 2016, in the Alsaial Alsagair village, and 385 samples of urine were collected and processed using ...