The harmful use of alcohol causes an estimated 2.5 million deaths every year, of which a significant proportion occur in the young. Alcohol use is the third leading risk factor for poor health globally. In response to harmful use of alcohol, World Health Organization developed a global strategy to reduce the harmful use of alcohol endorsed by the Sixty-third World Health Assembly in 2010. Paral...

The harmful use of alcohol inflicts great deal of social and economic losses on individuals and societies. Given the increase in world population and the predicted increase in alcohol consumption, the alcohol related burden of disease progressively catches higher ranks in the list of factors threatening humans' life. It has been considered that the social and economic burden related to alcohol ...

Examination of differences between primary alcohol and drug abusing adolescents can provide valuable direction to intervention efforts, though little research in this area has been conducted. The current study compared primary alcohol and primary drug abusing runaway adolescents who were randomly assigned to family therapy or treatment as usual. Baseline differences, as well as response to trea...

Past literature has established an association between children's alcohol-related behaviors and parents' use of and attitudes toward alcohol. However, most studies tend to measure parental use and attitudes through proxy, i.e. children's perception. It is not clear the extent to which actual parental use and attitudes influence children's alcohol behaviors. The current study directly used paren...

Experimental animal models are critical for understanding the genetic, environmental and neurobiological underpinnings of alcohol use disorders. Limited studies investigate alcohol-induced effects on behavior using free-choice paradigms. The aims of the present experiment were to study voluntary alcohol intake using a modified intermittent access paradigm, investigate the effects of voluntary a...

an efficient method is described for the mild and rapid tetrahydropyranylation of alcohols and phenols using a catalytic amount of n-chlorosaccharin (1 mol %) and 3, 4-dihydro-2h-pyran under solvent-free condition at room temperature. benzylic alcohols and phenols containing electron withdrawing or donating groups in various positions of phenyl ring, cinamyl alcohol, primary, secondary, tertiar...

Recovery of metabolites from fermentation broth by solvent extraction can be used to optimize fermentation processes. End-product reutilization, low product concentration and large volumes of fermentation broth and the requirements for large bioreactors, in addition to the high cost largely contributed to the decline in fermentative 2,3-butanediol production. Extraction can successfully be ...

the harmful use of alcohol causes an estimated 2.5 million deaths every year, of which a significant proportion occur in the young. alcohol use is the third leading risk factor for poor health globally. in response to harmful use of alcohol, world health organization developed a global strategy to reduce the harmful use of alcohol endorsed by the sixty-third world health assembly in 2010. paral...

Transdermal alcohol sensors continuously collect reliable and valid data on alcohol consumption in vivo over the course of hours to weeks. Transdermal alcohol readings are highly correlated with breath alcohol measurements, but transdermal alcohol levels lag behind breath alcohol levels by one or more hours owing to the longer time required for alcohol to be expelled through perspiration. By pr...