Non-invasive transcutaneous vagus nerve stimulation elicits similar therapeutic effects as invasive stimulation, offering a potential treatment alternative for wide range of diseases, including epilepsy. Here, we present novel, non-invasive the nerve, which is performed manually viscero-osteopathically on abdomen (voVNS). We explore impact short-term voVNS various local and global characteristi...

The enteric nervous system may have an important role in modulating gastrointestinal barrier response to disease through activation of enteric glia cells. In vitro studies have shown that enteric glia activation improves intestinal epithelial barrier function by altering the expression of tight junction proteins. We hypothesized that severe injury would increase expression of glial fibrillary a...

Classically, sympathetic and parasympathetic systems act in opposition to maintain the physiological homeostasis. In this article, we report that both systems work together to restrain systemic inflammation in life-threatening conditions such as sepsis. This study indicates that vagus nerve and cholinergic agonists activate the sympathetic noradrenergic splenic nerve to control systemic inflamm...

Changes in cochlear microphonics (CM) were observed by the injection f vegetative stimulants into the abdominal cavity, by the application f nicotine to the superior cervical ganglion, and by excision or electric stimulatian of the cervical sympathetic nerve and vagus nerve on guinea-pigs. 1) C. M. is reduced by the injection fatropine and acetylcholine while it is induced at the biginnig and t...

Abstract Date Presented 04/20/2023 Children with unilateral weakness may demonstrate improved functional goal achievement less dosage requirement when constraint-induced movement therapy (CIMT) is paired transcutaneous auricular vagus nerve stimulation (taVNS), indicating burden to participants and encouraging translation OT clinical practice. Primary Author Speaker: Patricia Coker-Bolt Additio...

BACKGROUND Recently, clinical observations reported the potential benefit of vagus nerve stimulation (VNS) for pediatric epilepsy. Transcutaneous auricular vagus nerve stimulation (ta-VNS) is a newer non-invasive VNS, making it more accessible for treating pediatric epilepsy, yet there is limited clinical evidence for its effectiveness. METHODS/DESIGN A three-center, randomized, parallel, con...

Aetna considers vagus nerve electrical stimulators medically necessary durable medical equipment (DME) for shortening the duration or reducing the severity of seizures in members with partial onset seizures who remain refractory to optimal anti-epileptic medications and/or surgical intervention, or who have debilitating side effects from anti-epileptic medications. (Note: Electronic analysis of...