Human coagulation factor V (FV) is an essential coagulation protein with functions in both the pro- and anticoagulant pathways. Failure to express and control FV functions can either lead to bleeding, or to thromboembolic disease. Both events may develop into a life-threatening condition. Since the first description of APC resistance, and in particular the description of the so-called factor V(...

Content-based image retrieval (CBIR) systemwith relevance feedback, which uses the algorithm for feature-vector (FV) dimension reduction, is described. Feature-vector reduction (FVR) exploits the clustering of FV components for a given query. Clustering is based on the comparison of magnitudes of FV components of a query. Instead of all FV components describing color, line directions, and textu...

We study the consistency and convergence of the cell-centered Finite Volume (FV) external approximation of H 0 (Ω), where a 2D polygonal domain Ω is discretized by a mesh of convex quadrilaterals. The discrete FV derivatives are defined by using the so-called Taylor Series Expansion Scheme (TSES). By introducing the Finite Difference (FD) space associated with the FV space, and comparing the FV...

BACKGROUND Parental support is a key influence on children's health behaviours; however, no previous investigation has simultaneously explored the influence of mothers' and fathers' social support on eating and physical activity in preschool-aged children. This study evaluated the singular and combined effects of maternal and paternal support for physical activity (PA) and fruit and vegetable c...

Opuntia plants grow naturally in areas where temperatures are extreme and highly variable in the day during the entire year. These plants survive through different adaptations to respond to adverse environmental conditions. Despite this capability, it is unknown how CAM photosynthetic activity and growth in Opuntia plantlets is affected by constant heat or cold. Therefore, the main objective of...

Despite knowing that fruit and vegetable (FV) intake promotes health and well-being, few U.S. adults meet current guidelines. Thus, understanding people's motivation for FV intake is important for predicting dietary behavior. Applying self-determination theory, the goal of this study was to examine the role of social support as a potential moderator of the link between autonomous and controlled...

High average-power free-electron lasers may be useful for pumping high peak-power solid-state laser-amplifiers. At very high peak-powers, the pump source for solid-state lasers is non-trivial: flash lamps produce thermal problems and are unsuitable for materials with short florescence-times, while diodes can be expensive and are only available at select wavelengths. FELs can provide pulse train...

Factor V (FV) deficiency is a rare bleeding disorder whose genetic basis has been described in a relatively small number of cases. Among a total of 12 genetic defects reported in severely or moderately severe deficient patients, 3 were missense mutations and in no case was the mechanism underlying the deficiency explored at the molecular level. In this study, a homozygous missense mutation at c...

Here, we investigated the influence of the variable fragment (Fv) of IgG antibodies on the binding to the neonatal Fc receptor (FcRn) as well as on FcRn-dependent pharmacokinetics (PK). FcRn plays a key role in IgG homeostasis, and specific manipulation in the crystallizable fragment (Fc) is known to affect FcRn-dependent PK. Although the influence of the antigen-binding fragment (Fab) on FcRn ...