Dementia developed in a patient with widespread neurologic manifestations; she died within 5 months. Pathologic findings showed granulomatous inflammation with caseation necrosis, foreign body-type giant cells, and proliferative endarteritis with vascular occlusions. Broad-range polymerase chain reaction identified Mycobacterium neoaurum as the possible pathogen. Central nervous system infectio...

Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant disease. Conjunctival telangiectasias and retinal vascular malformations are known ocular manifestations. We report here the first case of open angle glaucoma in a patient with HHT caused by a nonsense mutation, C471X in the ACVRL1 gene.

Two cases are presented with clinical manifestations and neuropsychological evaluations which confirm the diagnosis of transient global amnesia (TGA). Their interest lies in the fact that in both cases the episodes were a result of light traumas. It was proposed that TGA was triggered by vascular changes resulting from a mild (whiplash or head) trauma.

LTHOIJGH the association of bleeding teuideuicy with uremia has beeui recognized fon’ at least a century,n the exact (‘ause has miever 1)een clearly defined. Vascular damage has been suggested.2 This study includes assays of many hemostatic factors in twelve patients showing varying degrees of azotelllia with and without hemorrhagic manifestations. An abnormality in platelet function (thrombocy...

Conjunctival hemangioma over the age of 60 is rare, with few cases reported in the literature. We present a unique case of a conjunctival capillary hemangioma, adding to the sparse literature of this uncommon vascular tumor. Here, we present an interesting case of spontaneous development of this tumor at age 68, without associated systemic disease process or cutaneous manifestations.

Klippel-Trenaunay-Weber syndrome is characterized by limb hypertrophy, varicose veins, and vascular nevus. The orofacial manifestations include early eruption of permanent teeth and hemifacial hypertrophy. This 5-year-old male patient had facial asymmetry, limb abnormalities, and a thumb-sucking habit. Cephalometric analysis revealed a Class II open bite occlusion. (Pediatr Dent 16:231-35, 1994)

The vein of Galen aneurysmal malformation (VGAM) is an extremely rare arterio-venous malformation. The VGAM clinical manifestations vary depending on the magnitude of vascular compromise and the age at initial presentation. Neonates typically present with severe congestive heart failure. Here we present a case in which a systolic heart murmur was the first manifestation of high output heart fai...

A child showing signs of Henoch-Schönlein purpura developed a right tibiofibular vascular thrombosis. Antiphospholipid antibody tests were positive for both lupus anticoagulant and anticardiolipin antibodies. This suggests that an antiphospholipid syndrome should be considered in cases of Henoch-Schönlein purpura and antiphospholipid antibodies should be measured to determine whether prophylact...

The histologic appearance of a consecutive series of 200 neovascular membranes was analyzed. Specific angiographic manifestations of exudative age-related macular degeneration such as classic or occult choroidal neovascularization, vascularized pigment epithelial detachment, tear of the retinal pigment epithelium, polypoidal choroidal vasculopathy and deep retinal vascular anomalous complex cor...