background: hypertension is considered an independent risk factor for cardiovascular mortality in diabetic patients. the present study was designed to determine the role of gamma amino butyric acid b (gabab) receptor and l-arginine (l-arg) in gaba-induced vasorelaxation in normal and streptozotocin-induced diabetic rat vessels. methods: diabetes was induced by a single i.p. injection of strepto...

Objective(s): Multifunctional nanomedicine is the new generation of medicine, which is remarkably promising and associated with the minimum toxicity of targeted therapy. Distribution and transport of nanoparticles (NPs) in the blood flow are essential to the evaluation of delivery efficacy. Materials and Methods: In the present study, we initially designed a phantom based on Murray’s mini...

Background: Hypertension is considered an independent risk factor for cardiovascular mortality in diabetic patients. The present study was designed to determine the role of gamma amino butyric acid B (GABAB) receptor and L-arginine (L-Arg) in GABA-induced vasorelaxation in normal and streptozotocin-induced diabetic rat vessels. Methods: Diabetes was induced by a single i.p. injection of strepto...

Retina images are obtained from the fundus camera and graded by skilled professionals. However there is considerable shortage of expert observers has encouraged computer assisted monitoring. Evaluation of blood vessels network plays an important task in a variety of medical diagnosis. Manifestations of numerous vascular disorders, such as diabetic retinopathy, depend on detection of the blood v...

Diabetic Retinopathy is the most common cause of blindness in the working population of the western world and is very common among people who suffer from diabetes. Fortunately, during a clinical examination an ophthalmologist is able to determine the onset of the disease by taking certain features of the retinal vessels of the fundus into account. These features include the narrowing of vessels...