Asthma is a complex disease because its presentation can vary considerably from patient to patient. The nature of asthma often requires physicians to use a multifaceted approach to ensure optimal outcomes (i.e., control of symptoms) and to prevent asthma exacerbations and increased health care utilization. Evidence-based disease management guidelines have been developed and published to aid in ...

This article offers an account of embodied exchange with the world that associates conscious operations with actively inferring the causes of our sensations. Its agenda is to link formal (mathematical) descriptions of dynamical systems to a description of perception in terms of beliefs and goals. The argument has two parts: the first calls on the lawful dynamics of any (weakly mixing ergodic) s...

Cortical neurogenesis is a highly stereotyped process in which progenitor cells generate neurons destined for specific cortical layers depending on the timing of cell cycle exit. Previous work has shown that during corticogenesis, progenitors become progressively restricted in their developmental potential. Recent work has uncovered some of the intrinsic mechanisms that underlie this fate restr...