Vasculogenic mimicry (VM) is a blood supply modality that occurs independently of endothelial cell angiogenesis. Hypoxia and the epithelial-mesenchymal transition (EMT) induce VM formation by remodeling the extracellular matrix. Our previous study demonstrated that hypoxia-inducible factor-2 alpha (HIF-2α) promotes the progress of EMT in pancreatic cancer; however, whether HIF-2α promotes VM fo...

Initially, virtual machine (VM) meant a software abstraction with the looks of a computer system’s hardware. Now, VM can be seen as a layered abstraction over various places in the system including following levels of virtualization: hardware–level, operating system–level, and high–level language VMs. Hardware–level approach was the first attempt to implement virtualization. Several hardware VM...

A heat-stable enterotoxin produced by Vibrio mimicus (VM-ST) was studied. VM-ST was purified from a culture supernatant of V. mimicus strain AQ-0915 by ammonium sulfate fractionation, hydroxyapatite treatment, ethanol extraction, column chromatography on both SP-Sephadex C-50 and DEAE-Sephadex A-25, and HPLC, and the recovery rate was about 15%. Purified VM-ST was heat-stable. VM-ST activity wa...

The distribution, origin, and fine structures of cholecystokinin-8-like immunoreactive ( CCKI ) fibers in the nucleus ventromedialis hypothalami (vm) of the rat were examined using immunohistochemistry. CCKI fibers were moderately concentrated in the ventrolateral part of the vm, decreasing in number dorsomedially. However, no CCKI cells were seen in the vm even in colchicine-treated rats. In a...

Value management (VM) participants often encounter problems of lack of active participation and insufficient time and information in decision analysis. Group decision support systems (GDSS) have been proposed to overcome the above problems by improving efficiency and effectiveness of VM studies. In order to investigate the effect of using GDSS in VM workshops, three experimental studies togethe...

Trabecular shear stress magnitude and variability have been implicated in damage formation and reduced bone strength associated with bone loss for human vertebral bone. This study addresses the issue of whether these parameters change with age, gender or anatomical location, and if so whether this is independent of bone mass. Additionally, 3D-stereology-based architectural parameters were exami...

Live Virtual Machine (VM) migration across data centers is an important technology to facilitate cloud management and deepen the cooperation between cloud providers. Without the support of a shared storage system between data centers, migrating the storage data (i.e. virtual disk) of a VM becomes the bottleneck of live VM migration over WAN due to the contradiction between the low bandwidth of ...

Vasculogenic mimicry (VM) is a blood supply modality that is strongly associated with the epithelial-mesenchymal transition (EMT), TWIST1 activation and tumor progression. We previously reported that metastasis-associated in colon cancer-1 (MACC1) induced the EMT and was associated with a poor prognosis of patients with gastric cancer (GC), but it remains unknown whether MACC1 promotes VM and r...