Vulvar Morbus Paget (MP) represents a rare intraepithelial adenocarcinoma. It accounts for less than 1% of all vulvar neoplasia and usually appears in postmenopausal women. Histologically it is analogous to Paget's disease of the breast. The most common clinical symptom is pruritus. The lesion appears as an erythematous or as an eczematous lesion with islands of hyperkeratosis. Occasionally, si...

Syringomas are common intraepidermal sweat gland tumors most often found in women around the time of adolescence. Frequent sites of involvement include the lower eyelids and malar areas, however vulvar involvement is relatively rare. These lesions often present as small, multiple, skin-colored-to-yellowish papules and are often associated with increased vulvar discomfort and itching. We present...

Pregnancy following squamous cell carcinoma of the vulvar is rare. Its rarity is reflected by a paucity of cases reported in the literature. We report two cases of pregnancy following diagnosis and treatment for vulvar squamous cell carcinoma, and review eleven prior reported cases. In successfully treated vulvar cancer subsequent pregnancy is not shown to increase the risk of disease recurrenc...

Varicose veins are usually found on legs, but they also can be found in the vulva. Although, they are often considered as a cosmetic problem, they can lead to complications that results in lost time from work and lost wages. Treatment options include conservative, endovenous or interventional or surgical treatments. Because of rich vulvar vascular network, surgical procedures for vulvar varicos...

objective: to evaluate the adnexal masses with conventional gray scale and color doppler flow imaging and to assess their diagnostic reliability to differentiate benign and malignant adnexal masses. materials and methods: we evaluated 30 patients with adnexal mass. morphological characterization of the mass was done using sassone score. color doppler parameters noted down in each patient and ca...

OBJECTIVE To examine the prevalence of physical or sexual violence victimization among women referred to a specialty clinic for management of vulvar dysesthesia/vestibulodynia as compared to a healthy gynecology clinic population. STUDY DESIGN The subjects in this case-control study were women who had completed routine questionnaires prior to presentation to the University of Michigan Center ...

Background: Vulvar contact dermatitis is inflammatory disorders of genital skin causing itch, burning, and plaques with overlying excoriation and linear fissures. Objective: To assess the effectiveness of a soft foam based on Tiab® system (TF), complex of titanium micro crystals covalently bound with silver ions associated with hyaluronic acid, as a treatment of vulvar contact dermatitis. Metho...

Vulvar melanoma is the second most common vulvar cancer. Patients with vulvar melanoma usually present with the disease at a late stage and have a poor prognosis. The prognostic predictors reported in the literature are not unequivocal and the role of lichen sclerosus and c-KIT mutations in the aetiology of vulvar melanoma is unclear. Breslow staging currently seems to be the most adequate pred...

Vulvar cancer is the fourth most common gynecological cancer worldwide. However, limited studies have been completed on the molecular characterization of vulvar squamous cell carcinoma resulting in a poor understanding of the disease initiation and progression. Analysis and early detection of the precursor lesion of HPV-independent vulvar squamous cell carcinoma (VSCC), differentiated vulvar in...