PURPOSE Increased blood-brain barrier (BBB) permeability is radiologically detectable in regions affected by drug-resistant epileptogenic lesions. Brain penetration of antiepileptic drugs (AEDs) may be affected by BBB damage. We studied the effects of BBB damage on brain distribution of hydrophilic [deoxy-glucose (DOG) and sucrose] and lipophilic (phenytoin and diazepam) molecules. We tested th...

1. The highest surface pressure of phosphatidylcholine monolayers allowing penetration of delipidated serum albumin decreased in the order dibehenoyl>distearoyl>dipalmitoyl=dimyristoyl. This pressure was not related to the area occupied or to the space available between the phospholipid molecules at the interface. 2. Penetration of albumin into yeast phosphatidylcholine monolayers was increased...

OBJECTIVE To confirm a relationship between the pharyngeal response and bolus volume, and examine whether increasing the fluid bolus volume can improve penetration and aspiration for stroke dysphagic patients. METHODS Ten stroke patients with a delayed pharyngeal response problem confirmed by a videofluoroscopic swallowing study (VFSS) were enrolled. Each subject completed two swallows each o...

Full-field optical coherence microscopy (FFOCM) is an interferometric technique for obtaining wide-field microscopic images deep within scattering biological samples. FFOCM has primarily been implemented in the 0.8 mum wavelength range with silicon-based cameras, which may limit penetration when imaging human tissue. In this paper, we demonstrate FFOCM at the wavelength range of 0.9 - 1.4 mum, ...

deterioration of concrete structures in the gulf region is a serious problem. penetration of chloride ion into concrete is responsible for such early deterioration. determination of chloride diffusion coefficient is an effective way to predict the service life of concrete structures. in order to investigate the performance of concrete mixtures in such environments, ordinary and silica fume conc...

As regards if curing stops for some time and then resumes again, then strength gain will also stop and reactive, in this study with choose suitable curing conditions after improper first curing (recurring) for normal and silica-fume concrete, Effect of this curing conditions on strength and permeability was investigated. The results from tests such as compressive strength, capillary water absor...

The first signs of mobile commerce hype are here. Extremely rapid penetration and growth processes are predicted on the basis of some quick descriptions of mobile technology. The roots of these predictions are often found in markets with a low penetration rate of mobile technology. Nevertheless, it should be clear that without real substance in m-commerce products and services the investments i...

This paper gives an overview on the potentials of numerical simulations for understanding dynamics in laser material processing. After a short introduction into the model, simulation results on several processes like laser beam deep penetration welding, drilling or cutting are presented. Furthermore simulation results are compared with experimentally obtained data.

This paper analyzes the impact on mobile telephony diffusion patterns of the two predominant payment regimes, calling party pays (CPP) and receiving party pays (RPP), for mobile termination services. By applying instrumental variable techniques to panel data we account for a possible interdependency of penetration rates and regulatory interventions. For this purpose we use data on political and...