MICROBIOLOGY. For the article ‘‘A Mr 34,000 proinflammatory outer membrane protein (oipA) of Helicobacter pylori’’ by Yoshio Yamaoka, Dong H. Kwon, and David Y. Graham, which appeared in number 13, June, 20, 2000, of Proc. Natl. Acad. Sci. USA (97, 7533–7538), the authors note the following correction. The sequence of the HP0638 gene was incorrect as published. The sequence published was 59-GCT...

The effects of the proportion of concentrates in grass silage-based diets and of restricted dry matter (DM) intake were examined using 156 Simmental cross Friesian steers which were initially 389 kg live weight. The animals were reared on high-forage diets until 14 months of age and were then given grass silage ad libitum and supplemented with rolled barley which constituted (1) 0, (2) 120, (3)...

Under 5 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 64 10.4 5 to 9 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 68 11.1 10 to 14 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39 6.3 15 to 19 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 46 7.5 20 to 24 years . . . . . . . . . . . . . . . . . . . . . ....

The role of 39–59 exonucleases in double-strand break (DSB)-promoted recombination was studied in crosses of bacteriophage T4, in which DSBs were induced site specifically within the rIIB gene by SegC endonuclease in the DNA of only one of the parents. Frequency of rII recombinants was measured in two-factor crosses of the type i 3 ets1, where ets1 designates an insertion in the rIIB gene carry...

BACKGROUND Flexibility of food reward-related brain signaling (FRS) between food and nonfood stimuli may differ between overweight and normal-weight subjects and depend on a fasted or satiated state. OBJECTIVE The objective was to assess this flexibility in response to visual food and nonfood cues. DESIGN Twenty normal-weight [mean ± SEM BMI (in kg/m(2)) = 22.7 ± 0.2; mean ± SEM age = 22.4 ...

We conducted a multicenter study of the safety, tolerability, and plasma pharmacokinetics of the parenteral formulation of voriconazole in immunocompromised pediatric patients (2 to 11 years old). Single doses of 3 or 4 mg/kg of body weight were administered to six and five children, respectively. In the multiple-dose study, 28 patients received loading doses of 6 mg/kg every 12 h on day 1, fol...

Amino acids interact with glucose metabolism both as carbon substrates and by recycling glucose carbon via alanine and glutamine; however, the effect of protein intake on glucose homeostasis during weight loss remains unknown. This study tests the hypothesis that a moderate increase in dietary protein with a corresponding reduction of carbohydrates (CHO) stabilizes fasting and postprandial bloo...

A total of 135 measurements of polyfructoside clearance as a measure of glomerular filtration rate (GFR) were made in 39 infants of 25.5-33 weeks' gestation, birth weight 720-2000 g, between the ages of 0.5 and 33 days. GRF was related to postconceptional age and increased exponentially from geometric mean 0.59 ml/min at 26 weeks' postconceptional age to 1.40 ml/min at 33 weeks. GFR in the firs...

Background Patients with psoriatic disease(PsD) [psoriasis(PsO) and arthritis(PsA)] are at greater risk of non-alcoholic fatty liver disease(NAFLD) NAFLD-associated fibrosis/cirrhosis compared the general population other inflammatory arthritis(1) independent disease-modifying medications [biological(b)DMARDs or methotrexate(MTX)][2]. Conversely, using these in patients significant NAFLD might ...