نتایج جستجو برای: weight regain
تعداد نتایج: 352290 فیلتر نتایج به سال:
In your June editorial, “Is Blockade of Pancreatic Lipase the Answer?” (1), you suggest that the success of the 2-y clinical trials of orlistat is diminished by the propensity of obese patients to regain weight. I disagree. The North American Association for the Study of Obesity (NAASO) considers a weight loss of ≥ 5% to be clinically significant (2). In each of the published clinical trials of...
BACKGROUND Weight loss has been shown to reduce risk factors associated with cardiovascular disease and diabetes; however, successful maintenance of weight loss continues to pose a challenge. OBJECTIVE The present study was designed to assess whether changes in subcutaneous adipose tissue (scAT) gene expression during a low-calorie diet (LCD) could be used to differentiate and predict subject...
OBJECTIVE We evaluated long-term impact of sustained weight loss versus weight regain on cardiovascular risk factors in real-world clinical practice. METHODS We evaluated 129 obese patients with diabetes enrolled in Weight Achievement and Intensive Treatment (Why WAIT) program, a 12-week clinical model of intensive lifestyle intervention. After 1 year, we divided participants into group A, wh...
BACKGROUND Behavioral interventions for obesity produce clinically meaningful weight loss, but weight regain following treatment is common. Extended care programs attenuate weight regain and improve weight loss maintenance. However, less is known about the most effective ways to deliver extended care, including contact schedules. METHODS We compared the 12-month weight regain of an extended c...
BACKGROUND Long-term maintenance of weight loss remains a therapeutic challenge in obesity treatment. OBJECTIVE This multicenter, double-blind, placebo-controlled study was designed to test the hypothesis that orlistat, a gastrointestinal lipase inhibitor, is significantly more effective than a placebo in preventing weight regain. DESIGN Obese subjects who lost > or = 8% of their initial bo...
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