The R3230AC mammary carcinoma grows faster in diabetic rats; tumor cells from diabetic rats demonstrate increased proline transport and incorporation into pro teins compared to tumor cells obtained from intact rats. Tumor cells from insulin-treated diabetic rats showed a decreased rate of proline transport and a lower amount of proline incorporation, both of which were comparable to that in cel...

Posterior capsular opacification (PCO), the main complication of cataract surgery, is mainly caused by the proliferation, migration, and epithelial-mesenchymal transition (EMT) of the residual lens epithelial cells (LECs).Vitamin C was reported to reduce the risk of forming a cataract. However, there has been no study showing the association between vitamin C and PCO. In this study, we found th...

Intracellular accumulation of the amino acid proline has previously been linked to the salt tolerance and virulence potential of a number of bacteria. Taking advantage of the proBA mutant Escherichia coli CSH26, we identified a listerial proBA operon coding for enzymes functionally similar to the glutamyl kinase (GK) and glutamylphosphate reductase (GPR) enzyme complex which catalyzes the first...

abstract the purpose of this research was to transform two economically important cultivars of strawberry with p5cs gene, which encodes δ1-pyrroline-5-carboxylate synthetase (p5cs), the key enzyme in proline biosynthesis. shoots were obtained on ms basal medium supplemented with 2% glucose and 4 mg/l tdz for camarosa and kurdistan cultivars. for genetic transformation, a binary vector pbi121 co...

in this research, the effect of air pollution on proline concentration, soluble sugar, anatomical and morphological features was studied in two plant species malva parviflora and hordeum glaucum in 2009. the area of the stand steel factory of khuzestan was considered as the polluted site and shush region was considered as the control site, and sampling was carried out from the two sites, accide...

1. Ornithine delta-transaminase (l-ornithine-2-oxo acid aminotransferase, EC 2.6.1.13) and Delta(1)-pyrroline-5-carboxylate reductase [l-proline-NAD(P) 5-oxidoreductase, EC 1.5.1.2] were demonstrated in fat-body and flight-muscle tissues of the silkmoth Hyalophora gloveri. Arginase (l-arginine ureohydrolase, EC 3.5.3.1) is also present in these tissues. 2. Arginase, ornithine transaminase and p...

Salinity is a major yield reducing factor in coastal as well as arid irrigated rice production systems. Salt induced abiotic stress is an acute problem, interrupting the metabolic processes of plants, resulting in reduced growth and productivity. Proline is an amino acid which increases in plants under abiotic stress. Salinity stress affects the metabolism of plants leading to severe crop damag...

Fusarium wilt diseases caused by the fungus Fusarium oxysporum lead to significant yield losses of crops. Biocontrol agents such asTrichoderma viride , Trichoderma harzianum and Pseudomonas fluorescens are applied to control Fusarium wilt of Arachis hypogaea. Experiments were conducted on the effect of culture filtrates of T.viride (1%), T.harzianum (1.5%), and P. fluorescens (2%) on biochemica...

Exogenously provided proline has been shown to serve as an osmoprotectant in Bacillus subtilis. Uptake of proline is under osmotic control and functions independently of the known transport systems for the osmoprotectant glycine betaine. We cloned the structural gene (opuE) for this proline transport system and constructed a chromosomal opuE mutant by marker replacement. The resulting B. subtil...