PMEL is a pigment cell-specific protein that forms physiological amyloid fibrils upon which melanins ultimately deposit in the lumen of the pigment organelle, the melanosome. Whereas hypomorphic PMEL mutations in several species result in a mild pigment dilution that is inherited in a recessive manner, PMEL alleles found in the Dominant white (DW) chicken and Silver horse (HoSi)--which bear mut...

Abstrak: Masyarakat Dusun merupakan kaum peribumi yang majoriti di negeri Sabah. Kepercayaan asal masyarakat ini adalah pagan dipengaruhi oleh unsur-unsur animisme. Namun, sejak kedatangan agama Islam Sabah bermula sekitar abad ke-15 Masihi, secara perlahan-lahan, sedikit sebanyak mula beralih kepada Islam. Di Sabah, penempatan utama daerah Ranau. Daerah Ranau terbahagi tiga Dewan Undangan Nege...

in the linear system ax = b the points x are sometimes constrained to lie in a given subspace s of column space of a. drazin inverse for any singular or nonsingular matrix, exist and is unique. in this paper, the singular consistent or inconsistent constrained linear systems are introduced and the effect of drazin inverse in solving such systems is investigated. constrained linear system arise ...

Abstract Introduction Ultrasound is used to diagnose pregnancy complications such as miscarriage and fetal health conditions. Within the UK, findings identified during ultrasound examination are delivered by sonographers standard. However, little known about experiences of when delivering unexpected news (DUN), impact this has on them, or their preferences for training delivery. Methods Qualita...

Given a $\sigma $-finite infinite measure space $(\Omega ,\mu )$, it is shown that any Dun\-ford–Schwartz operator $T: \mathcal {L}^1(\Omega )\to )$ can be uniquely extended to the $\mathcal )+\mathcal {L}^\infty (

The objective of the present study was to evaluate the antidepressant action of Withania somnifera (WS) as well as its interaction with the conventional antidepressant drugs and to delineate the possible mechanism of its antidepressant action using forced swimming model in mice. Effect of different doses of WS, fluoxetine and imipramine were studied on forced swimming test induced mean immobili...