With some amazement I read the recent article of Wolfson et al. [1] on the comparison of the latent periods of multiple sclerosis (MS) in different populations. In MS only the age at the onset of the disease is known, albeit often with considerable uncertainty. The authors compare two samples of MS patients, from France and from Canada, for which the ages at the onset of the disease are virtual...

A computer system has been developed to manage 3D medical brain images based on their contents. These images, mainly in the form of PET (Positron Emission Tomography) or MR (Magnetic Resonance) modalities were provided by Wolfson Brain Image Centre (WBIC) at Cambridge, and have been diagnosed with lesions. The characteristics of these lesions, including head injury, tumors, Alzheimer's Diseases...

The evaluation of beta-adrenergic blockade in cardiac arrhythmias is difficult because of the complex nature of the arrhythmias and the varied modes of action of blocking drugs. Studies have confirmed the therapeutic value of the betaadrenergic blocking drug pronethalol (Alderlin) (Vaughan Williams, 1963 ; Stock and Dale, 1963 ; Payne and Senfield, 1964; Wolfson et al., 1966) and its more poten...

Aglaia Ntokou,* Friederike Klein,* Daria Dontireddy, Sven Becker, Saverio Bellusci, William D. Richardson, Marten Szibor, Thomas Braun, Rory E. Morty, Werner Seeger, Robert Voswinckel,* and Katrin Ahlbrecht* Department of Lung Development and Remodelling, Max Planck Institute for Heart and Lung Research, Member of the German Center for Lung Research [Deutsches Zentrum für Lungenforschung (DZL)]...

R controlled trials, when appropriately designed, conducted, and reported, represent the gold standard in evaluating healthcare interventions. However, randomized trials can yield biased results if they lack methodological rigour.1 To assess a trial accurately, readers of a published report need complete, clear, and transparent information on its methodology and findings. Unfortunately, attempt...

Moving objects databases (MODs) provide the framework for the efficient storage and retrieval of the changing position of continuously moving objects. This includes the current and past locations of moving objects and the support of spatial queries that refer to historical location information and future projections as well. Nowadays, new spatiotemporal applications that require tracking and re...

A convenient method for direct photometric determination of total globulin in serum has been developed using a one-tube, one.reagent system. The analysis is based on a variation of the Hopkins-Cole reaction, in which glyoxylic acid condenses with the tryptophan residues present in globulin to produce a purple color. In the presence of copper and under the conditions of the analysis, color inten...

Moving objects databases (MODs) provide the framework for the efficient storage and retrieval of the changing position of continuously moving objects. This includes the current and past locations of moving objects and the support of spatial queries that refer to historical location information and future projections as well. Nowadays, new spatiotemporal applications that require tracking and re...

The annual testicular cycle of the European Starling, Sturnus uulgaris, follows the general pattern of many photoperiodic avian species of the north temperate zone. That is, the onset of testicular growth is associated with increasing daily photoperiods following the winter solstice. Captive starlings maintained under natural daylengths at 38” N achieve testicular maturation by mid-April, with ...

Abstract This article provides a reconsideration of Gregory Nazianzen’s account the Christological union by analysing Gregory’s conception as ‘mixture’ (μίξις) or ‘blending’ (κρᾶσις). While scholars have long recognized that conceives Christ’s humanity and divinity kind ‘mixture’, there is disagreement to which philosophical understanding mixture—if any—underlies this conception. Three rival in...