Let Fq be a finite field of q = pm elements with characteristic p. A polynomial P(x) ∈ Fq[x] is called a permutation polynomial of Fq if P(x) induces a bijective map from Fq to itself. In general, finding classes of permutation polynomials of Fq is a difficult problem (see [3, Chapter 7] for a survey of some known classes). An important class of permutation polynomials consists of permutation p...

An anti-holomorphic multiplication by the integers Od of a quadratic imaginary number field, on a principally polarized complex abelian variety AC is an action of Od on AC such that the purely imaginary elements act in an anti-holomorphic manner. The coarse moduli space XR of such A (with appropriate level structure) is shown to consist of finitely many isomorphic connected components, each of ...

The xylose-fermenting recombinant Saccharomyces cerevisiae and its improvement have been studied extensively. The redox balance between xylose reductase (XR) and xylitol dehydrogenase (XDH) is thought to be an important factor in effective xylose fermentation. Using protein engineering, we previously successfully reduced xylitol accumulation and improved ethanol production by reversing the depe...

Let R = Z4 be the integer ring mod 4. A double cyclic code of length (r, s) over R is a set that can be partitioned into two parts that any cyclic shift of the coordinates of both parts leaves invariant the code. These codes can be viewed as R[x]-submodules of R[x]/(xr −1)×R[x]/(xs−1). In this paper, we determine the generator polynomials of this family of codes as R[x]-submodules of R[x]/(xr −...

Extended-release (XR) formulations enable less frequent dosing vs. conventional (e.g., immediate release (IR)) formulations. Regulatory registration of such formulations typically requires pharmacokinetic (PK) and clinical efficacy data. Here we illustrate a model-informed, exposure-response (E-R) approach to translate controlled trial data from one formulation to another without a phase III tr...

JPEG XR is a draft international standard undergoing standardization within the JPEG committee, based on a Microsoft technology known as HD Photo. One of the key innovations in the draft JPEG XR standard is its integer-reversible hierarchical lapped transform. The transform can provide both bit-exact lossless and lossy compression in the same signal flow path. The transform requires only a smal...

Atypical antipsychotics have become a widely utilized component of the bipolar disorder treatment armamentarium, with approximately 45% of bipolar patients prescribed atypicals. Over the last decade all atypical drugs except for clozapine have received a Food and Drug Administration (FDA) bipolar indication. In October 2008, the FDA approved quetiapine XR monotherapy for the treatment of acute ...

This work evaluated the effect of dissolved oxygen and the initial inoculum concentration on xylose reductase (XR) production by Candida guilliermondii from sugarcane bagasse hemicellulosic hydrolysate. Both the parameters were studied under an experimental design 2 with triplicate at central point. The statistical analysis of the results indicated a significant negative effect on XR production...

Restless Legs Syndrome (RLS) is a common condition associated with many medical illnesses and medications. Psychotropic medications (both antidepressants and antipsychotics) may be causal. There have been over twenty cases of RLS due to Quetiapine but no published case reports linking RLS to Quetiapine XR. We present the case of a woman with previously established Bipolar Disorder who presented...

Monolayers of lipids have been studied for more than a century. During the past decade new insight into the field has resulted from the development of surface sensitive X-ray scattering methods utilizing synchrotron radiation: grazing-incidence X-ray diffraction (GIXD) and specular X-ray reflectivity (XR). These novel methods provide direct microscopic information about the systems in question ...