An interest in the field of algicides for swimming pools has led to a survey of the problems involved in this field. A study of the bactericidal and algicidal properties of some of the chemicals used has been reported (Fitzgerald, 1959) in which it was pointed out that some of the products available show remarkable properties in laboratory tests. The present studies demonstrate how the activity...

objective: development of high producing mammalian cell lines is a major bottleneck in manufacturing of recombinant therapeutic proteins. this study examines the effect of using the matrix attachment region from the human interferon beta gene in combination with promoter activation strategy with e1a 13s protein on human tissue plasminogen activator (t-pa) expression in chinese hamster ovary (ch...

One of the central players in the complex regulation of flowering, CONSTANS (CO), functions as a center for integration of the various signals that determine the timing of flowering. As output, CO regulates the expression of FLOWERING LOCUS T (FT) and other genes (reviewed in Shim et al., 2017). COcontainsaCCT(CONSTANS,CONSTANSLIKE, TOC1)domainsimilar to theconserved domain in NF-YA, a subunit ...

BACKGROUND Lutein is a hydroxy-carotenoid constituting the macular pigment of the human retina. Increasing lutein intake from foods could increase the density of this pigment and decrease the risk of developing macular degeneration. Yellow carrots are a novel food source that could increase lutein consumption. OBJECTIVE We evaluated and compared lutein uptake and clearance in humans from gene...

Increasing feelings of satiety may reduce appetite and energy intake. The role of inulin consumption in impacting satiety is unclear. A randomised double-blind controlled crossover trial aimed to determine the effects of inulin+yogurt on satiety after 1 and 8-d consumption. The preload breakfast included 100 g vanilla yogurt with (yogurt-inulin (YI)) and without (yogurt-control (YC)) 6 g inulin...

The zinc (Zn(++)) transporter ZnT8 plays a crucial role in zinc homeostasis. It's been reported that an acute decrease in ZnT8 levels impairs β cell function and Zn(++) homeostasis, which contribute to the pathophysiology of diabetes mellitus (DM). Although ZnT8 expression has been detected in the retinal pigment epithelium (RPE), its expression profile in the retina has yet to be determined. F...

This study aimed to investigate the mechanism of hypoxia-inducible factor-1 alpha (HIF-1α) mediated hypoxia-induced permeability changes in bladder endothelial cells. Models of in vitro hypoxic cell culture of bladder cancer, bladder cancer cells with low HIF-1α expression and HIF-1α RNA interference (RNAi) expression vector were established. Western blot and reverse transcription polymerase ch...

The dynamics of buoyant water entering a rotating basin are studied using a series of laboratory experiments designed to elucidate the alongshore transport mechanisms in river plumes. Inflowing water, which is discharged perpendicular to the tank wall, is observed to form a growing anticyclonic bulge and a coastal current downstream of the bulge. Detailed simultaneous measurements of the veloci...

We study fragments of a μ-calculus over data words whose primary modalities are ‘go to next position’ (Xg), ‘go to previous position’ (Yg), ‘go to next position with the same data value’ (Xc), ‘go to previous position with the same data value (Yc)’. Our focus is on two fragments that are called the bounded mode alternation fragment (BMA) and the bounded reversal fragment (BR). BMA is the fragme...