Chapter 1: Overview of Zinc Nutrition ............................................................................................................... S99 1.1 Biological functions of zinc ............................................................................................................................. S99 1.2 Tissue zinc distribution and reserves .........................................

We now recognize three distinct motifs of DNA-binding zinc proteins: (i) zinc fingers, (ii) zinc clusters, and (iii) zinc twists. Until very recently, x-ray crystallographic or NMR three-dimensional structure analyses of DNA-binding zinc proteins have not been available to serve as standards of reference for the zinc binding sites of these families of proteins. Those of the DNA-binding domains ...

Previous studies of the yeast Saccharomyces cerevisiae indicated that the vacuole is a major site of zinc storage in the cell. However, these studies did not address the absolute level of zinc that was stored in the vacuole nor did they examine the abundances of stored zinc in other compartments of the cell. In this report, we describe an analysis of the cellular distribution of zinc by use of ...

BACKGROUND Food acidulants, β-carotene-rich vegetables and sulfur compound-rich Allium spices are known to improve zinc bioaccessibility from food grains. This animal study evaluated the positive influence of these promoters of zinc bioaccessibility on zinc status during zinc repletion in Wistar rats previously rendered zinc-deficient by feeding a zinc-deficient semi-synthetic diet for 4 weeks....

Methanol dehydrogenase from the thermotolerant Bacillus sp. C 1 was studied by electron microscopy and image processing. Two main projections can be distinguished: one exhibits 5-fold symmetry and has a diameter of 15 nm, the other is rectangular with sides of 15 and 9 nm. Subsequent image processing showed that the 6-fold view possesses mirror symmetry. The rectangular views can be divided int...

Many secreted bioactive signaling molecules, including the yeast mating pheromones a-factor and alpha-factor, are initially synthesized as precursors requiring multiple intracellular processing enzymes to generate their mature forms. To identify new gene products involved in the biogenesis of a-factor in Saccharomyces cerevisiae, we carried out a screen for MA Ta-specific, mating-defective muta...

Many secreted bioactive signaling molecules, including the yeast mating pheromones a -factor and a -factor, are initially synthesized as precursors requiring multiple intracellular processing enzymes to generate their mature forms. To identify new gene products involved in the biogenesis of a -factor in Saccharomyces cerevisiae , we carried out a screen for MAT a -specific, mating-defective mut...

Electroplating and metalworking industries discharge large amounts of heavy metals, including copper (Cu), nickel (Ni) and zinc (Zn) ions, in their effluents have been recognized as a major problem to human health and aquatic life. Copper is highly toxic because it is non biodegradable and carcinogenic, Copper has been reported to cause neurotoxicity commonly known as “Wilson’s disease” due to ...

This study provides an up to date review of tannins, specifically quebracho, in mineral processing and metallurgical processes. Quebracho is a highly useful reagent in many flotation applications, acting as both a depressant and a dispersant. Three different types of quebracho are mentioned in this study; quebracho “S” or Tupasol ATO, quebracho “O” or Tupafin ATO, and quebracho “A” or Silvafloc...

Zinc is essential for multiple aspects of metabolism. Physiologic signs of zinc depletion are linked with diverse biochemical functions rather than with a specific function, which makes it difficult to identify biomarkers of zinc nutrition. Nutrients, such as zinc, that are required for general metabolism are called type 2 nutrients. Protein and magnesium are examples of other type 2 nutrients....