The effects of the antiestrogen tamoxifen (TAM) on the growth of two hormone-sensitive human tumors have been examined in athymic mice. The endometrial tumor, EnCalOl, was stimulated to grow by TAM either alone or when combined with estradiol. This contrasted with the nonstimulation of the breast tumor, MCF-7, by TAM alone and the antago nist action of TAM on estradiol-stimulated growth of MCF-...

The years 1895 to 1898 were momentous for their impact on health and human well beings. First, Wilhelm Roentgen noted a glowing fluorescent screen, caused by invisible rays. This event subsequently led to the discovery of X-rays in 1895, and thus the birth of the “atomic age”. Next Becquerel’s investigations of these mysterious rays led to his experiments with uranium salt crystals. He th...

Administration of nickel carbonyl to rats inhibited RNA synthesis by a chromatin-RNA polymerase complex prepared from lysed hepatic nuclei. Rats were killed 6 hr after i.v. administration of Ni(CO)4 in LDSO dosage (2.2 mg Ni/100 g body weight). The rate of RNA synthesis by the chromatinRNA polymerase complex from Ni(CO)4-treated rats averaged 0.16 (S.E. = ±0.02, N = 18) ¿/mole cytidine tripho...

â φα = αφα , with α a complex number (see next page for a discussion of â and â†). Such a state is called a “coherent state”. Coherent states turn out to be the closest quantum analog of classical states with well-defined amplitudes and phases, and are extremely important in e.g. the quantum mechanical description of laser light, radio cavities, Bose-Einstein condensates, and just about everyth...

Let A be a commutative unital C-algebra and let  denote its Gelfand spectrum. We find some necessary and sufficient conditions for a nondegenerate representation of A to be unitarily equivalent to a multiplicative representation on a space L(Â, μ), where μ is a positive measure on the Baire sets of Â. We also compare these conditions with the multiplicity-free property of a representation.