Streptococcus pyogenes (group A Streptococcus; GAS) causes clinical diseases, including pharyngitis, scarlet fever, impetigo, necrotizing fasciitis and streptococcal toxic shock syndrome. A number of group A streptococcus vaccine candidates have been developed, but only one 26-valent recombinant M protein vaccine has entered clinical trials. Differing from the design of a 26-valent recombinant ...

Streptococcus pyogenes appears to be almost exclusively restricted to humans, with few reports on isolation from animals. We provide a detailed characterization (emm typing, pulsed-field gel electrophoresis [PFGE], and multilocus sequence typing [MLST]) of 15 S. pyogenes isolates from animals associated with different clinical backgrounds. We also investigated erythromycin resistance mechanisms...

OBJECTIVE Several studies of group A streptococci (GAS) have revealed that a small number of dominant resistant clones might be responsible for the spread of Streptococcus (S.) pyogenes resistance to macrolides. We aimed to determine the genetic diversity of macrolide resistant group A streptococci (MRGAS), isolated from patients with pharyngitis in Serbia. MATERIALS AND METHODS The clonal re...

Infection of the skin or throat by Streptococcus dysgalactiae subspecies equisimilis (SDSE) may result in a number of human diseases. To understand mechanisms that give rise to new genetic variants in this species, we used multi-locus sequence typing (MLST) to characterise relationships in the SDSE population from India, a country where streptococcal disease is endemic. The study revealed India...

Streptococcus pyogenes, or group A Streptococcus, is a pathogen responsible for a wide range of clinical manifestations, from mild skin and soft tissue infections and pharyngitis to severe diseases. Its epidemiological characteristics should be comprehensively under surveillance for regulating the national prevention and treatment practice. Herein, a total of 140 S. pyogenes, including 38 invas...

Scarlet fever was associated with feared outbreaks and mortality in the 19th Century. It occurs sporadically in modern society and infection is readily treated with antibiotics. We report on a scarlet fever outbreak in children attending a primary school in Perth, Western Australia, in late 2003. A total of 13 cases were identified over a five week period. Six of the cases were pre-primary chil...

Eikonalised minijet model analysis of σ inel γγ. Abstract We study the theoretical predictions for the total inelastic γγ cross-sections, with an emphasis on the eikonalised minijet model (EMM). In the context of the EMM, we discuss a new ansatz for the overlap function involving the photons. We discuss the dependence of the EMM predictions on various input parameters as well as predictions for...

In this note we address the issue of theoretical estimates of the hadronic cross-sections for γγ processes. We compare the predictions of the minijet model with data as well as other models, highlighting the band of uncertainties in the theoretical predictions as well as those in the final values of the σ(γγ → hadrons) extracted from the data. We find that the rise of σ γγ with energy shown in ...

1. Mobile device management (MDM): MDM is a platform life cycle management technology that provides inventory, OS configuration management, mobile app provisioning and deprovisioning, remote wipe, and remote viewing/control for troubleshooting. MDM profiles, installed on the device, facilitate these functions. 2. Mobile application management (MAM): MAM applies management and policy control fun...

To overcome shortcomings of Exact Matching Method (EMM) and Substitute Description Method (SDM), an Inexact Matching Method Based on Ontology and Semantic Distance (OSDIMM) is introduced. This method, firstly, describes resources information with Ontology languages to get Resource Ontology Description (RODs); then, infers Concept Hierarchy Trees and Property Hierarchy Trees from RODs; lastly, c...