Abstract Background There is a growing interest in transcriptomics studies parallel to the advancement of transcriptome databases and bioinformatics, which provided opportunity study responses growths, stimuli stresses. an increase demand for excellent RNA extraction techniques. General protocols can be used extraction, but quality quantity vary different types tissues from organisms. Hence, sp...

Mal de Meleda is a rare autosomal recessive transgredient keratoderma .Onset is in early childhood, and the development of hyperkeratosis is preceded by erythema. Patches of waxy ivory-yellow hyperkeratosis extend across the whole palms and soles, and on to the dorsal surfaces of hands and feet. Similar lesions of knees and elbows may develop. We describe an 18 year old man with the diagnosis o...

Analysis of four nearby transpositions of Ac from the waxy locus indicate that the element can reinsert to either side. The cause of the asymmetry observed for P-VV transpositions is discussed and a model is presented to account for the high frequency of close reinsertions of Ac.

Yaumatei Dermatological Clinic, 12/F, Yaumatei Specialist Clinic, 143 Battery Street, Kowloon A 58-year-old woman presented with multiple itchy, skin-coloured, waxy papules over her face, back, chest and limbs for one year. The histology revealed papular mucinosis with marked fibrosis. Her thyroid function was normal and serum protein electrophoresis detected a kappa monoclonal band. Therefore,...