نتایج جستجو برای: سلول های کشنده طبیعی nk cell
تعداد نتایج: 2185123 فیلتر نتایج به سال:
PURPOSE Renal cell carcinoma harbors high numbers of infiltrating lymphocytes with apparent limited efficacy in tumor control. This study focused on the natural killer (NK) cells infiltrating renal cell carcinoma. EXPERIMENTAL DESIGN Tumor-infiltrating lymphocytes (TIL) were isolated from renal cell carcinoma and analyzed for NK cell frequency and phenotype (n = 34). NK cells were enriched an...
Abstract Natural killer (NK) cells have been implicated in Ebola virus disease (EVD) pathogenesis as well protection against viruses. A clear understanding of their role during EVD is needed for better exploiting functionalities designing effective countermeasures Previously, we reported that protein VP40 induces IL-12 and IL-18 dependent activation human NK involves accessory cells. Here, exte...
سابقه و هدف: صمغ آنغوزه دارای خواص دارویی بوده و مطالعات اثرات ضد سرطانی و آنتی اکسیدانی آن را اثبات کرده است. این مطالعه با هدف بررسی اثرات سایتوتوکسیک عصاره صمغ آنغوزه بر ﺳﻠﻮل ﻫﺎی ﻛﺎرﺳﻴﻨﻮﻣﺎی ﻛﺒﺪ اﻧﺴﺎن انجام شد. مواد و روش ها: در این مطالعۀ تجربی عصاره صمغ آنغوزه بر سلول های سرطانی HepG2 و طبیعی L929اثر داده شد. محیط کشت RPMI حاوی L-گلوتامین، پنی سیلین، استرپتومایسین و 10 درصد FBS بوده و 24، 4...
SummarySézary syndrome (SS) is a rare, leukemic type of cutaneous T-cell lymphoma (CTCL), for which extracorporeal photopheresis (ECP) first-line therapy. Reliable biomarkers to objectively monitor the response ECP in patients with SS are missing. We examined quantitative and qualitative impact on natural killer (NK) cell activity patients, especially their functional ability antibody-dependent...
Received: 17 April, 2009 Accepted: 18 Nov, 2009 Abstract: Background & Aims: Rheumatoid Arthritis is an inflammatory disease. The cause is yet unknown. It is possible that in causing the disease immunological responses be involved. The aim of this study was to compare CD29+T lymphocytes and NK cells in rheumatoid arthritis patients and healthy people. Materials & Methods: In this study twe...
چکیده ندارد.
In humans, NK cells are mainly identified by the surface expression levels of CD56 and CD16, which differentiate between five functionally different NK cell subsets. However, nowadays NK cells are considered as a more heterogeneous population formed by various subsets differing in function, surface phenotype, and anatomic localization. In human CMV- and hantaviruses-infected subjects, an increa...
Galectin-9 is a b-galactoside binding lectin with expressed immunoregulatory activity. During pregnancy galectin-9 produced by trophoblast cells and regulates the function of natural killer (NK) at maternal-fetal interface via to Tim-3 (T-cell Ig mucin domain-containing protein 3) molecules. Natural lymphocytes belong innate lymphoid cells, which have cytotoxic effect on target are capable prod...
شیوه های مرسوم درمان سرطان بر ریشه کن کردن سلول های توموری، از طریق شیمی درمانی و رادیوتراپی، و فعال سازی سیستم ایمنی برای از بین بردن سلول های توموری تاکید دارد. با آنکه این شیوه های درمانی در برخی سرطان ها پاسخ خوبی داشته است، لازم است درمان های اختصاصی تری برای بیمارانی که به درمان های معمول پاسخ نمی دهند، ابداع شود. به علاوه باید از آسیب بافت های نرمال، که به دنبال درمان های معمول ایجاد می ...
The literature suggests that effective defence against tumour cells requires contributions from both Natural Killer (NK) and CD8+ T cells. NK are spontaneously active infected target cells, whereas take some times to activate cell called as cell-specific targeting, kill the virus. interaction between has produced other cell, tumour-specific We illustrate tumour–immune through mathematical model...
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