Correct use of an adrenalin auto-injector (AAI) is vital in an emergency situation where a person has gone into anaphylactic shock. Studies have shown that nearly half of untrained participants are unable to correctly use an AAI training device after instruction. Emerade is an AAI with a different design for use, with pictures providing instructions. This study aimed to assess intuitiveness and...

The aim of this study was to evaluate the left ventricular mechanical dyssynchrony (LVMD) and left ventricular dysfunction of patients in AAI, DDD and VVI pacing modes using real-time three-dimensional echocardiography (RT3DE) and tissue Doppler imaging (TDI). The results from the RT3DE and TDI were subsequently compared. Twenty patients with sick sinus syndrome (SSS) who had undergone the impl...

Half of the severe asthma patients suffer from uncontrolled exacerbations. Our work in neuro-immunology has shown that, context asthma, vagal nociceptor neurons drive a feed-forward inflammatory loop with lung immune cells, and that silencing these reverses allergic airway inflammation (AAI). Here, we aim to expand findings clinically relevant model pollution exacerbated asthma. Experimental al...

Abstract. Fathoni A, Hudiyono S, Cahyana AH, Ilyas M, Purnaningsih I, Agusta A. 2023. Anticandidal and antioxidant potencies of endophytic fungi associated with Tinospora crispa. Biodiversitas 24: 2547-2555. Natural products including fungi, have opportunities for medicinal uses as anticandidal agents. This study aimed to investigate the activities isolated from Brotowali (Tinospora crispa (L.)...

BACKGROUND C1 posterior arch screw placement is one of the most effective treatments for atlantoaxial instability (AAI), which can be performed by either pedicle or lateral mass screw fixation. This study attempted to compare the feasibility and clinical outcomes of C1 pedicle with lateral mass screw fixations for treatment of AAI with C1 posterior arches >4 mm. METHODS A total of 140 patient...

INTRODUCTION Alcohol is an important factor weighting towards global disease burden, premature death and Disability-Adjusted Life Years. This study examines the burden imposed on the Borgo Trento Verona Hospital Emergency Department (ED) Italy by patients with Acute Alcohol Intoxication (AAI). METHODS A 6-year retrospective study was performed by reviewing medical records in all patients (≥ 1...

This work was undertaken to ascertain to what degree the physical appearance of a Brazilian individual was predictive of genomic African ancestry. Using a panel of 10 population-specific alleles, we assigned to each person an African ancestry index (AAI). The procedure was able to tell apart, with no overlaps, 20 males from northern Portugal from 20 males from São Tomé Island on the west coast ...

We investigated attachment representations and the capacity for mentalization in a sample of adult female borderline patients with and without comorbid narcissistic personality disorder (NPD). Participants were 22 borderline patients diagnosed with comorbid NPD (NPD/BPD) and 129 BPD patients without NPD (BPD) from 2 randomized clinical trials. Attachment and mentalization were assessed on the A...

Various pacing technologies have been developed during the past 50 years since the first pacemaker was implanted in 1958. Dual-chamber pacing, rate responsiveness, programmable and rate-responsive atrioventricular (AV) intervals, alternative-site pa0cing, and new multichamber pacing devices are all attempts to mimic normal cardiac physiology as much as feasible. The categories of alternative-si...