نتایج جستجو برای: عوامل انگیزشی erg
تعداد نتایج: 120380 فیلتر نتایج به سال:
TMPRSS2 and SLC45A3 rearrangements may coexist in the same tumor. ERG rearrangements and PTEN loss are concomitant events in prostate cancer (PrCa), and can cooperate in progression. We have reported that mRNA expression of TMPRSS2-ERG and SLC45A3-ERG rearrangements plus PTEN loss define an aggressive tumor subset. The aim of this study has been to validate these results by immunohistochemistry...
Over the last two decades, many attempts have been made to record electroretinograms (ERG) of human macula by several investigators. However, previous ERG responses were not informative enough, because each ERG component could not be evaluated independently. However, we have developed a new system for recording focal macular ERG where we can evaluate all ERG components. This paper reviews what ...
in modern pharmacological medicine, saffron is used for various purposes due to its antioxidant effect. this study evaluated retinal function after treatment with saffron supplementation during a follow-up period of 6 months to provide further insight into the efficacy and safety considerations of this treatment. sixty patients with wet or dry age-related macular degeneration (amd) were randoml...
مقدمه: بیماری عروق کرونر به عنوان اولین علت عمده ی مرگ و میر در جمعیت ایران به شمار می رود. یکی از روش هایی که اخیراً برای تغییر عوامل خطر بیماری عروق کرونر نیز به کار رفته است، مصاحبه ی انگیزشی است. طبق نظریه ی خود تعیین گری، نیازهای بنیادی روان شناختی خود مختاری، شایستگی و ارتباط با دیگران در مصاحبه ی انگیزشی مورد حمایت قرار می گیرند. در این پژوهش سعی می شود اثربخشی مصاحبه ی انگیزشی بر ارضای ن...
BACKGROUND TMPRSS2:ERG gene aberration may be a novel marker that improves risk stratification of prostate cancer before definitive cancer therapy, but studies have been inconclusive. METHODS The study cohort consisted of 202 operable prostate cancer Slovenian patients who underwent laparoscopic radical prostatectomy. We retrospectively constructed tissue microarrays of their prostatic specim...
Osteopontin (OPN) is an extracellular matrix glycophosphoprotein that plays a key role in the metastasis of a wide variety of cancers. The high level of OPN expression in prostate cells is associated with malignancy and reduced survival of the patient. Recent studies on prostate cancer (PCa) tissue have revealed recurrent genomic rearrangements involving the fusion of the 5' untranslated region...
Recently, ETS-related gene (ERG) gene rearrangements, phosphatase tensin homologue (PTEN) deletions and EGFR family aberrations were characterized as potential biomarkers for prostate cancer (PCa) patient management. Although ERG gene rearrangement has been identified in approximately 50% of localized prostate cancers in western countries, the prognostic significance of this critical molecular ...
Osteopontin (OPN) is an extracellular matrix glycophosphoprotein that plays a key role in the metastasis of a wide variety of cancers. The high level of OPN expression in prostate cells is associated with malignancy and reduced survival of the patient. Recent studies on prostate cancer (PCa) tissue have revealed recurrent genomic rearrangements involving the fusion of the 50 untranslated region...
PURPOSE We aimed to analyze whether ERG rearrangement in biopsies could be used to assess subsequent cancer diagnosis in high-grade prostatic intraepithelial neoplasia (HGPIN) and the risk of lymph node metastasis in early prostate cancer. EXPERIMENTAL DESIGN Samples from 523 patients (361 with early prostate cancer and 162 with HGPIN) were collected prospectively. On the basis of the cutoff ...
BACKGROUND There is limited evidence that supports etiologically distinct molecular subtypes of prostate cancer, the identification of which may improve prevention. Given their antioxidant properties, we hypothesized that lycopene and tomato sauce may be especially protective against diseases harboring the common gene fusion transmembrane protease, serine 2 (TMPRSS2):v-ets avian erythroblastosi...
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