XIII

For the assay of blood-clotting Factor XIII (Fibrin-Stabilizing Factor, FSF), the antibody-neutralization test (Bohn and Haupt, 1968), the monodancylcadaverine incorporation test (Lorand et al., 1969; Nishimura et al., 1975) and the Laurell method are tried in our country (Hidano et al., 1975). None of them, however, could be applied to the clinical screening for Factor XIII-deficient cases; th...

A congenital deficiency of the coagulation Factor XIII A subunit (F XIII A) is a rare autosomal recessive disorder that is characterized by a life-long bleeding tendency complicated by a difficulty in healing. Thus far, no molecular genetic analysis of this disorder has been reported. In this study, we demonstrate the molecular abnormalities in a family with this disorder. We performed Northern...

The Park Place Economist, Volume XIII

....................................................................................................................... I PREFACE......................................................................................................................... III LIST OF PUBLICATIONS...............................................................................................VII LIST OF FIGURES ..........

..... ............................................................................................................... X Acknowledgements ...................................................................................................XII Declaration... .......................................................................................................... XIII Chapter