CONTEXT The tryptophan hydroxylase 2 (TPH2) gene encodes the first (also the rate-limiting) enzyme in the serotonin biosynthetic pathway. Despite reports of possible associations between polymorphisms in human TPH2 and many psychiatric disorders, including bipolar disorder (BPD), the functional effect and susceptibility loci of such polymorphisms for BPD have not yet been identified. OBJECTIV...

Controlled laboratory microcosms were used to research the phytoremediation potential of lupines (Lupinus chamissonis) for hydrocarbon-contaminated groundwater at a former oil field near Guadalupe, California. During oil production in the Guadalupe Oil Field, a kerosene-like hydrocarbon mixture was used as a diluent to improve the flow of the heavy crude oil. Leaking tanks and pipes resulted in...

The rostral ventromedial medulla (RVM) forms part of a descending pathway that modulates nociceptive neurotransmission at the level of the spinal cord dorsal horn. However, the involvement of descending RVM systems in opioid analgesia are a matter of some debate. In the present study, patch-clamp recordings of RVM neurons were made from rats that had received retrograde tracer injections into t...

BACKGROUND Suicidal behavior is a leading cause of injury and death worldwide. Several studies have provided a possible relationship between genetic factors and suicidal behavior. Also, these studies have shown evidence for altered serotonergic neural transmission in the pathogenesis of suicidal behavior. In addition, genes pertaining to the serotonergic system have been proposed as candidates ...

so far, different methods have been applied to clean up soils contaminated with oil. bioremediation is one of the clean up technologies which uses microorganisms or microbial processes to degrade oil contaminations in soils. this study evaluates the applicability of cow manure as bioremediation alternative for soils spiked with petroleum hydrocarbons. target contaminant of this research was die...

in this work, ferric coagulation and acid cracking as olive mill wastewater (omw) pretreatments during photocatalysis process were compared in batch recirculation reactor. as ferric ions influence, ferric coagulation has preference over acid cracking. ferric ions influence on intensification of penolic components absorption on tio2 surfacein initial and oxidize organic pollutant during photocat...

Interaksi sinergis antara tanaman-bakteri dapat digunakan untuk meningkatkan kinerja fitoremediasi tanah yang terkontaminasi hidrokarbon (HC). Penelitian bertujuan karakterisasi plant growth promoting rhizobacteria: Azotobacter sp. dan Pseudomonas dalam limbah minyak bumi menggunakan tanaman sorgum (Sorghum bicolor L.). rancangan acak kelompok faktorial (RAK-Faktorial) terdiri dari inokulasi se...

Colorectal visceral hypersensitivity has been demonstrated in a subset of irritable bowel syndrome (IBS) patients. Serine protease and serotonergic signaling modulate gastrointestinal visceral sensitivity. We evaluated whether altered mucosal serine protease and serotonergic pathway components are related to rectal visceral hypersensitivity in IBS patients. Colorectal mucosal biopsies of 23 IBS...

The objective of this study was to evaluate the proximal composition, as well as Total Antioxidant Capacity (TAC) and Total Phenols (TPH) in meals that represent a complex food matrix, from different hospitals in Bolivia and Sweden. Protein, fat, ash, dietary fiber and carbohydrate contents were measured in 29 samples: 20 from two Bolivian hospitals and 9 from the university hospital in Lund, S...

In the present study, we assessed the agro-industrial performance of 22 sugarcane genotypes adaptable to edaphoclimatic conditions in production microregions in the State of Pernambuco, Brazil, and we recommended the commercial cultivation of select genotypes. The variables analyzed were as follows: sucrose percentage in cane juice, tonnage of saccharose per hectare (TPH), sugarcane tonnage per...