We use the available radio, optical and X-ray measurements for the afterglows of the short bursts 050709 and 050724 to constrain the blast-wave energy, its collimation and the density of the circumburst medium. For GRB 050709 (whose duration was 0.07 s), we identify two kinds of models: i) a high-density solution, where the ejecta are collimated in a jet of half-angle θjet > 6 and interact with...

Granzyme B (GrB) and perforin (PFN) are the major components of cytoplasmic granules contained in immune cellular effectors. The granule secretory pathway is one of the mechanisms by which these cells exert their cellular cytotoxicity. Recently, it has been reported that GrB and PFN are also present in circulating hemopoietic CD34(+) progenitor cells mobilized by chemotherapy and granulocyte-co...

Human B cells are currently not known to produce the proapoptotic protease granzyme B (GrB) in physiological settings. We have discovered that BCR stimulation with either viral Ags or activating Abs in the context of the acute phase cytokine IL-21 can induce the secretion of substantial amounts of GrB by human B cells. Importantly, GrB response to viral Ags was significantly stronger in B cells...

Using a simple off-axis jet model of GRBs, we can reproduce the observed unusual properties of the prompt emission of GRB 980425, such as the extremely low isotropic equivalent γ-ray energy, the low peak energy, the high fluence ratio, and the long spectral lag when the jet with the standard energy of ∼ 10 ergs and the opening half-angle of 10 . ∆θ . 30 is seen from the off-axis viewing angle θ...

Optical and infrared monitoring of the afterglow site of gamma-ray burst (GRB) 031203 has revealed a brightening source embedded in the host galaxy, which we attribute to the presence of a supernova (SN) related to the GRB (" SN 031203 "). We present details of the discovery and evolution of SN 031203 from 0.2 to 92 days after the GRB, derived from SMARTS consortium photometry in I and J bands....

We predict the rate at which Gamma-Ray Burst (GRB) afterglows should be detected in supernova searches as a function of limiting flux. Although GRB afterglows are rarer than supernovae, they are detectable at greater distances because of their higher intrinsic luminosity. Assuming that GRBs trace the cosmic star formation history and that every GRB gives rise to a bright afterglow, we find that...

The supernova SN 2006aj associated with GRB 060218 is the second-closest GRB-SN observed to date (z=0.033). We present Very Large Telescope, Liverpool Telescope, and Katzman Automatic Imaging Telescope multi-color photometry of SN 2006aj. This supernova is found to be subluminous and rapidly evolving. Its early light curve includes an additional wavelength-dependent component, which can be inte...

Trichoderma is an antagonist fungus used in agriculture and forestry for the diseases control. The use of herbicides metsulfuton methyl glyphosate a common practice weed control that limits use. This study has evaluated toxic effects ofthe metsulfuron on four strains fungi genus (GRB-HA1, GRB-HA2, GRB-HA8 GRB-HA9). Poisoned media were prepared with high doses 25 mL·L-1 + 0.2 g L-1 (D500) low 12...

We present the SVOM (Space-based multi-band astronomical Variable Object Monitor) mission, that is being developed in cooperation between the Chinese National Space Agency (CNSA), the Chinese Academy of Science (CAS) and the French Space Agency (CNES), and is expected to be launched in 2013. Its scientific objectives include the study of the GRB phenomenon (diversity and unity), GRB physics (pa...

We exposed primary CD8(+) T cells to soluble CD3 mAb plus IL-2 and limited numbers of monocytes (3%). These cells were activated but concurrently subjected to ongoing apoptosis ( approximately 25% were apoptotic from day 2 of culture). However, their costimulated CD4(+) counterparts were much less prone to apoptosis. The apoptotic signaling pathway bypassed Fas and TNFRs, and required the activ...