Meta modeling is a widely established means for developing conceptual modeling methods (CMM). Here, we show how a CMM for the structured conceptual design of management information systems has been developed in an evolutionary process based on meta modeling. The aim of management information systems is to satisfy the information need managers have to successfully accomplish their tasks. The qua...

BACKGROUND Celiac disease (CD) carries an increased risk of several malignancies, including cancers of the gastrointestinal tract and hematologic malignancies. The disease course of cutaneous malignant melanoma (CMM) is affected by the immune status of the host, and therefore may be associated with CD. OBJECTIVE We sought to test for an association between CD and CMM in a population-based set...

The establishment of the diagnosis of cutaneous malignant melanoma (CMM) always calls for histopathological confirmation. Further to the recognition of the CMM aspects, immunohistochemistry is helpful, in particular, in determining the size of the replicative compartment and the activity in each of the cell cycle phases (G(1), S, G(2), M). The involvement of cancer stem cells and transient ampl...

Anatomic M-mode (AMM) is an echocardiographic technique that is capable of generating M-mode studies from two-dimensional (2D) cine loops. Unlike conventional M-mode (CMM) whose scan line must lie along the axis of the ultrasound signal, AMM produces M-mode studies independent of the orientation of the ultrasound beam. We sought to determine the ability of AMM to measure cardiac dimensions in n...

This paper describes the case study of an application of the Capability Maturity Model (CMM) to a micro team with less than 10 people and very limited resources, clearly placed in the first CMM level of maturity, the Initial level. A major aim of the case, which extended over a period of one year, was to study the extent to which the CMM could be adapted to very small teams for software process...

An estimated 10% of all cutaneous malignant melanoma (CMM) cases are inherited, but the genetics of familial CMM are largely unknown. Ocular malignant melanoma (OMM), which is rare, may be associated with familial CMM. We performed a genome-wide scan of two Danish pedigrees with multiple cases of OMM (N = 10) and CMM (N = 3) and other malignancies (with no germline mutations in CDKN2A, CDK4, BR...

The Software CMM The Software Engineering Institute at Carnegie Mellon University developed the SW-CMM as a model for building organizational capability, and it has been widely adopted in the software community and beyond. As Table 1 shows, the SW-CMM is a five-level model that describes good engineering and management practices and prescribes improvement priorities for software organizations. ...