OBJECTIVE At 5 to 6 years of age, body fatness normally declines to a minimum, a point called adiposity rebound (AR), before increasing again into adulthood. We determined whether a younger age at AR was associated with an increased risk of adult obesity and whether this risk was independent of fatness at AR and parent obesity. DESIGN A retrospective cohort study using lifelong height and wei...

Depending on stoichiometry, reactions of the mixed valence Sn(0)/Sn(III) compound Sn(SnAr(3))(2) (1) (Ar = C(6)H(4)(O(i)Pr)(2)-2,6) with the likewise substituted plumbylene PbAr(2) (3) afforded either the homoleptic distannylplumbylene Pb(SnAr(3))(2) (4) or the heteroleptic arylstannylplumbylene Pb(Ar)SnAr(3) (5), a valence isomer of a stannaplumbene.

We present a detailed examination of the features of the Ac-3 tive Region (AR) NOAA 10798. This AR generated coronal mass ejections 4 (CMEs) that caused a large geomagnetic storm on 24 August 2005 with the 5 minimum Dst index of −216 nT. We examined the evolution of the AR and 6 the features on/near the solar surface and in the interplanetary space. The 7 AR emerged in the middle of a small cor...

Source and Description of Primers. Primers were designed from published bovine and human androgen receptor (AR) sequences (GenBank accession number Z75315 and M27430, respectively). These primers were used to obtain a porcine sequence (submitted to GenBank: accession number AF079783). A total of 247 bp out of the entire 793-bp PCR product shared 90.3% identity with sections of exons 7 and 8 of ...

Much fewer mice lacking androgen receptor (AR) in the entire body develop bladder cancer (BCa). However, the role of urothelial AR (Uro-AR) in BCa development remains unclear. In the present study, we generated mice that lacked only Uro-AR (Uro-AR(-/y)) to develop BCa by using the carcinogen BBN [N-butyl-N-(4-hydroxybutyl)-nitrosamine] and found that Uro-AR(-/y) mice had a lower incidence of BC...

Histone deacetylase inhibitors (HDACIs) can disrupt the viability of prostate cancer (PCa) cells through modulation of the cytosolic androgen receptor (AR) chaperone protein heat shock protein 90 (HSP90). However, toxicities associated with their pleiotropic effects could contribute to the ineffectiveness of HDACIs in PCa treatment. We designed hybrid molecules containing partial chemical scaff...

Reaction of the azidoborate salt [N(n-Bu)(4)][(C(6)F(5))(3)B(N(3))] ([N(n-Bu)(4)][1]) with the uranium(III) tris(anilide) complex (THF)U(N[t-Bu]Ar)(3) (2; THF = tetrahydrofuran; Ar = 3,5-Me(2)C(6)H(3)) results in formation of the paramagnetic uranium(V) nitridoborate complex [N(n-Bu)(4)][(C(6)F(5))(3)BNU(N[t-Bu]Ar)(3)] ([N(n-Bu)(4)][3]). Chemical oxidation of [N(n-Bu)(4)][3] is facile and provi...

The purpose of this study was to examine the impact hydrophobicity, surface chemistry and topography on bacterial microalgal adhesion. To end, effects plasma treatments (argon (Ar) tetrafluorocarbon (CF 4 )) polycarbonate substrates bioadhesion were investigated in vitro. Surfaces characterized by goniometry, atomic force microscopy X-ray photoelectron spectroscopy. Two marine strains, a hydrop...

Allergic rhinitis (AR) is one of the most common allergic diseases, which adversely affect patients' quality of life. Mahuang Fuzi Xixin decoction (MFXD) has been widely used to treat AR in clinics in Asian countries. This study investigated the effect and possible therapeutic mechanisms of MFXD in the treatment of AR. A Wistar rat model of ovalbumin- (OVA-) induced AR was established and then ...