Aging is associated with learning deficits and a decrease in neuronal excitability, reflected by an enhanced post-burst afterhyperpolarization (AHP), in CA1 hippocampal pyramidal neurons. To identify the current(s) underlying the AHP altered in aging neurons, whole-cell voltage-clamp recording experiments were performed in hippocampal slices from young and aging rabbits. Similar to previous rep...

Metrifonate, a cholinesterase inhibitor, has been shown to enhance learning in aging rabbits and rats, and to alleviate the cognitive deficits observed in Alzheimer's disease patients. We have previously determined that bath application of metrifonate reduces the spike frequency adaptation and postburst afterhyperpolarization (AHP) in rabbit CA1 pyramidal neurons in vitro using sharp electrode ...

In order to process the assessment information more exactly and make the decision result more understandable in linguistic setting, a hybrid approach integrating OWA aggregation into VIKOR for multiple attributive group decision making in 2-tuple linguistic setting is proposed. In the method, the OWA is used to aggregate the linguistic assessment information. According to the ideas of VIKOR, th...

CA1 pyramidal neurons from animals that have acquired hippocampal tasks show increased neuronal excitability, as evidenced by a reduction in the postburst afterhyperpolarization (AHP). Studies of AHP plasticity require stable long-term recordings, which are affected by the intracellular solutions potassium methylsulphate (KMeth) or potassium gluconate (KGluc). Here we show immediate and gradual...

Pyramidal neurons in the piriform cortex from olfactory-discrimination-trained rats have reduced postburst afterhyperpolarization (AHP), for 3 days after learning, and are thus more excitable during this period. Such AHP reduction is caused by decreased conductance of one or more of the calcium-dependent potassium currents, I(AHP) and sI(AHP), that mediate the medium and slow AHPs. In this stud...

We identified a new form of activity-dependent modulation of the afterhyperpolarization (AHP) in tactile (T) sensory neurons of the leech Hirudo medicinalis. Repetitive intracellular stimulation with 30 trains of depolarizing impulses at 15-s inter-stimulus interval (ISI) led to an increase of the AHP amplitude (~60% of the control). The enhancement of AHP lasted for >/=15 min. The AHP increase...

With the effects of COVID-19 pandemic, e-commerce trend is driving faster, significantly impacting supply chains around world. Thus, importance logistics and chain functions has been amplified in almost every business that ships physical goods. In Vietnam, service sector seen rapid expansion. Since more businesses are seeking third-party (3PL) providers to outsource functions, this article aims...

Previous review papers on analytic hierarchy process (AHP) and TOPSIS (Technique for Order Preference by Similarity to Ideal Solution) mainly focused on the application areas and paid scant attention to the framework development of AHP, TOPSIS and their hybrid methods. The purpose of this paper is to review the literature on analytic hierarchy process (AHP), type of scale used in AHP, modified ...

Interval number is a useful tool to handle the uncertainty brought by human factors in multi-criteria decision-making (MCDM) process. When faced with MCDM problems in real-world, the experts may be uncomfortable giving precise upper and lower bounds of the interval ratios on multi-criteria. Based on the reciprocal judgment matrices given by the experts through pairwise comparisons, the satisfac...