BACKGROUND Less than one third of patients with fatal pulmonary embolism (PE) are identified prior to autopsy. OBJECTIVE To determine whether the clinical syndromes of acute PE are effective at identifying patients who die of this condition. METHOD Seven hundred seventy-eight autopsy reports at the Buffalo General Hospital from 1991 to 1996 inclusive were reviewed. Inpatient medical records...

INTRODUCTION Premature ejaculation (PE) is common. However, it has been underreported and undertreated. AIMS To determine the prevalence of PE and to investigate possible associated factors of PE. METHODS This cross-sectional study was conducted at a primary care clinic over a 3-month period in 2008. Men aged 18-70 years attending the clinic were recruited, and they completed self-administe...

BACKGROUND Studies conducted in animal models and humans suggest the presence of a dynamic equilibrium of amyloid-β (Aβ) peptide between cerebrospinal fluid (CSF) and plasma compartments. OBJECTIVE To determine whether plasma exchange (PE) with albumin replacement was able to modify Aβ concentrations in CSF and plasma as well as to improve cognition in patients with mild-moderate Alzheimer's ...

Introduction Bronchopulmonary sequestration (BPS) may cause prenatal pleural effusion (PE) or even hydrops. This case describes a fetus presenting with severe PE, which prenatally waned completely under steroid treatment, yet surprisingly reappeared rapidly after birth, requiring early surgical intervention. Case description A male fetus was diagnosed with left BPS and severe PE. After three ...

BACKGROUND Pulmonary embolism (PE) is a common and potentially life-threatening disorder. Patients with PE often have nonspecific symptoms, and the diagnosis is often delayed. AIM The aim of our study was to investigate the role of signal peptide-complement C1r/C1s, Uegf, and Bmp1-epidermal growth factor domain-containing protein 1 (SCUBE1) used in the diagnosis of PE. METHODS The study was...

Malignant tumors are often complicated with venous thrombosis and pulmonary embolism (PE), particularly in lung cancer. However, owing to the limited data regarding the clinical course about PE in lung cancer patients, the aim of this study is to analyze the risk factors and prognosis of patients with PE and lung cancer. We performed a retrospective case-control study, the clinical data of 90 p...

Pathogenic microbes acquire the human plasma protein plasminogen to their surface. In this article, we characterize binding of this important coagulation regulator to the respiratory pathogen nontypeable Haemophilus influenzae and identify the Haemophilus surface protein E (PE) as a new plasminogen-binding protein. Plasminogen binds dose dependently to intact bacteria and to purified PE. The pl...

Studies have reported inconsistent evidence for an association between venous thrombosis and arterial cardiovascular events. We further studied the association between both diseases by comparing the occurrence of cardiovascular events in patients diagnosed with acute pulmonary embolism (PE) contrasted to patients with comparable baseline risk characteristics (patients in whom PE was clinically ...

OBJECTIVE The first aim was to investigate specific signature patterns of metabolites that are significantly altered in first-trimester serum of women who subsequently developed preeclampsia (PE) compared to healthy pregnancies. The second aim of this study was to examine the predictive performance of the selected metabolites for both early onset [EO-PE] and late onset PE [LO-PE]. METHODS Thi...

Myxococcus xanthus cells exhibit directed motility up phosphatidylethanolamine (PE) gradients, and we suggest that PE behaves as a chemoattractant. Computer-assisted stop-motion digital microscopy was used to record cell movements in slide culture. PE decreased cellular reversal frequency with molecular specificity that was correlated with the fatty acid composition. Synthetic dilauroyl (di C12...