We examined the topology of angiotensin-converting enzyme (ACE) mRNA expression, activity, and shedding in myocardial infarction-induced heart failure and sought to elucidate the source of the increased plasma ACE activity in this model. Three months after coronary ligature, lung, scar, and remaining viable left ventricular tissues were analyzed for ACE mRNA expression as well as tissue and sol...

Ectopic pregnancy overall is the leading cause of death in the first trimester [1]. The incidence of pregnancy implantation in unusual sites, like cesarean scar is rising due to increased incidence of cesarean sections, pelvic inflammatory disease and dilatation and curettage [2]. Up to 72% of cesarean scar pregnancies occur in women who have had 2 or more cesarean deliveries [3-5]. The dehisce...

Breast cancer developing from a surgical scar is rare; this type of malignancy has been reported in only 12 cases to date. Herein, we report on a 52-year-old female who developed infiltrating ductal carcinoma in a surgical scar following excision of a benign mass. Two years previously, the patient underwent surgery and radiotherapy for invasive ductal carcinoma of the contralateral breast. The ...

OBJECTIVE To report the clinical characteristics, pathologic findings and treatments of a patient with a Caesarean scar choriocarcinoma. PATIENT HISTORY A 22-year-old woman had a diagnosis of primary gestational choriocarcinoma in a uterine Caesarean scar misdiagnosed as a normal Caesarean scar pregnancy. The patient underwent selective uterine artery embolization coupled with methotrexate ar...

PURPOSE We report the case of a patient with scar sarcoidosis that developed along a previous eyelid scar. There was no evidence of ocular or systemic sarcoidosis. METHODS A 29-year-old man presented with a mass on his right eyelid that had been present for two month. On ocular examination an erythematous, firm, and non-tender mass was diffusely palpable along the upper and lower eyelid scar....

Methods Caesarean scar pregnancy occurs due to implantation within a caesarean scar that is completely surrounded by myometrium and is therefore considered by many to be a late complication of caesarean section. The incidence of a caesarean scar pregnancy varies from 1 in 1800 to 1 in 2216 pregnancies and is rising due to an increase rates of the c section. Caesarean scar pregnancies are challe...

Although hypertrophic scarring commonly occurs following burns, many aspects such as incidence of and optimal treatment for scar hypertrophy remain unclear. This review will focus on hypertrophic scar formation after burn in particular, exploring multiple treatment options and describing their properties as well as effectiveness. To evaluate treatment efficacy and scar development, clinical sca...