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Electron microscopy can provide accurate, high-resolution images of the distribution of electrostatic potential (ESP) in biological macromolecules. Careful examination of ESP maps that have been published for peptides and proteins at resolution ranging from 1.0 Å to 2.9 Å reveals that the negative charges of carboxylate groups have a profound effect on their appearance. It is clear that investi...

Embedded scalable platforms (ESP) are a novel generation of platform architectures that yield optimal energy-performance operations while supporting a diversity of embedded application workloads. A companion methodology combines full-system simulation, pre-designed HW/SW interface libraries, high-level synthesis and FPGA prototyping to enable an effective design-space exploration which is drive...

The Clinton Administration has implied that short-run failures to control health care costs may cause a reexamination of wage and price controls as elements of comprehensive health care reform. The most recent imposition of mandatory wage and price controls was the Economic Stabilization Program (ESP) of the early 1970s. We analyze trends in hospitals' economic behavior and utilization before, ...

Evolutionary algorithms have been applied with great success to the difficult field of multi-objective optimisation. Nevertheless, the need for improvements in this field is still strong. We present a new evolutionary algorithm, ESP (the Evolution Strategy with Probabilistic mutation). ESP extends traditional evolution strategies in two principal ways: it applies mutation probabilistically in a...

Some measures of re l ig iosity, bel ief in an after l i fe , and bel ief in psychic phenomena were included in eight forced-choice ESP experiments. Seven of the experiments consisted of 40 trials of clairvoyance as a computer game and 40 trials of precognition in a paper-and-pencil test for each subject; and in one experiment there were 80 trials of clairvoyance. A combined measure of religios...

A multiplex PCR for the simultaneous detection of five virulence genes (asa1, gelE, cylA, esp, and hyl) in enterococci was developed. The presence of these genes was investigated in 153 clinical and 118 fecal Enterococcus faecium isolates from inpatients at an increased risk of developing infections (such as patients in intensive care units and hematology wards) from 13 hospitals in eight Europ...

BACKGROUND Enterococcus faecalis is an opportunistic pathogen that causes most of the enterococcal infections. Among the different factors implicated in the pathogenesis of these organisms, biofilm formation and antibiotic resistance are the most important. The ability for biofilm formation has been attributed to the presence of some virulence genes. However, no definite correlation has been fo...